Results 171 to 173 of about 221,149 (173)
British Journal of Pharmacology, EarlyView.Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange +7 more
wiley +1 more source
Dupilumab Efficacy and Safety in Patients With Persistent Asthma: Asia–Pacific Region
Clinical &Experimental Allergy, EarlyView.Asthma prevalence is increasing in the Asia–Pacific region, and this population is frequently underrepresented in phase 3 clinical studies. We demonstrate Dupilumab's efficacy and safety among patients with uncontrolled moderate‐to‐severe type 2 asthma.
Qingling Zhang +13 more
wiley +1 more source
Time to weight plateau with tirzepatide treatment in the SURMOUNT‐1 and SURMOUNT‐4 clinical trials
Clinical Obesity, EarlyView.Summary The rate of weight reduction during obesity treatment declines over time and eventually reaches a weight plateau. We investigated factors associated with time to weight plateau (TTWP) in tirzepatide‐treated participants with obesity or overweight in a post‐hoc analysis of SURMOUNT‐1 and SURMOUNT‐4 trials.
Deborah B. Horn +9 more
wiley +1 more source