Results 41 to 50 of about 55,552 (255)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Towards Positive Energy Districts

open access: yesInternational Sustainable Energy Conference - Proceedings
Positive energy districts (PEDs) are a vision to enable and foster the energy transition in the building sector. The integration of heat pumps (HP) in buildings and districts to achieve a net positive energy balance is crucial. The efficiency of the electric and thermal energy system of districts can be improved with the use of HPs. This refers to both,
Fabian Ochs   +4 more
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The deep renovation of high-rise apartment buildings to create positive-energy neighborhood

open access: yesFrontiers in Energy Research
Decarbonizing cities requires transforming existing high-density residential districts into low-carbon or Positive Energy Neighborhood (PENs). This is particularly challenging in cold climates, where high seasonal heat demand, limited solar availability,
T. Kalamees   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Positive Energy District (PED) Selected Projects Assessment, Study towards the Development of Further PEDs

open access: yesEnvironmental and Climate Technologies, 2021
Positive Energy District (PED) is a relatively new concept from which many projects are planned, however, only a few cases are currently close to be materialized, therefore, in this study the PED projects in operation and in implementation process in ...
Rueda Castellanos Sofia, Oregi Xabat
doaj   +1 more source

Holistic assessment methodology for Positive Energy Districts

open access: yesActa Polytechnica CTU Proceedings, 2022
Globally, cities are responsible for most of the world’s energy consumption and most of the carbon dioxide emissions. Therefore, the efficient transformation of urban energy systems is becoming a crucial step towards carbon neutrality and more effective ...
Jakub Kvasnica, Kateřina Válková
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Sustainable Development of Energy, Water and Environmental Systems and Smart Energy Systems

open access: yesInternational Journal of Sustainable Energy Planning and Management, 2022
This 34th volume of the International Journal of Sustainable Energy Planning and Management includes papers from the 2021 conference on Sustainable Development of Energy, Water and Environmental Systems (SDEWES) held October 10-15, 2021, in Dubrovnik ...
Poul Alberg Østergaard   +3 more
doaj   +1 more source

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