Results 41 to 50 of about 15,603 (248)
An Exploratory Study on Swedish Stakeholders’ Experiences with Positive Energy Districts
Energies, 2023 Positive energy district (PED) is a novel idea aimed to have an annual surplus of renewable energy and net zero greenhouse gas emissions within an area.
Moa Mattsson +4 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Autonomous Cyber-Physical Systems Enabling Smart Positive Energy Districts
Applied SciencesThe European Union (EU) is striving to achieve its goal of being climate-neutral by 2050. Aligned with the European Green Deal and in search of means to decarbonize its urban environments, the EU advocates for smart positive energy districts (PEDs). PEDs
Dimitrios Siakas +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Energies, 2023 More than half of the world population live in urban settlements which are responsible for a large share of energy consumption and, consequently, carbon emissions.
Mattia De Rosa +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Positive energy districts and energy communities: how living labs create value
Buildings & CitiesUrban living labs (ULLs) are experimental governance mechanisms accelerating sustainability transitions in the built environment, yet their governance implications and systemic impact are often under-examined.
Elena Malakhatka +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Energies, 2021 There are international activities and on-going initiatives, particularly at the European level, to define what Positive Energy Districts should be, as the driving concept for the urban transition to a sustainable future. The first objective of the paper
Jaume Salom +15 more
doaj +1 more source