Results 71 to 80 of about 15,603 (248)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Multi-dimensional self-assessment matrix and scoring system for Positive Energy Districts

Frontiers in Sustainable Cities
IntroductionA predominant portion of current Positive Energy District (PED) projects focuses on technical advancements, often neglecting non-technical aspects, which can hinder a just energy transition.
Bahanur Nasya, Yilmaz Vurucu, Batuhan Akkaya, Danny Nedkova, Gireesh Nair, Juveria Shah, Juveria Shah, Mengjie Han, Mengjie Han, Xingxing Zhang, Xingxing Zhang   +10 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Economic Impact Assessment for Positive Energy Districts: A Literature Review

Energies
To address the global challenge of sustainable energy transition in cities, there is a growing demand for innovative solutions to provide flexible, low-carbon, and socio-economically profitable energy systems.
Marco Volpatti, Andreas Tuerk, Camilla Neumann, Ilaria Marotta, Maria Beatrice Andreucci, Matthias Haase, Francesco Guarino, Rosaria Volpe, Adriano Bisello   +8 more
doaj   +1 more source

Urban Digital Twins Empowering Energy Transition: Citizen-Driven Sustainable Urban Transformation towards Positive Energy Districts [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Both citizens and authorities play a crucial role in the successful implementation of Positive Energy Districts (PEDs). However, the current public participation methods often fail to facilitate interactive knowledge production in the context of energy ...
V. Coors, R. Padsala
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Positive energy districts solution booklet

, 2021
Positive Energy Districts (PEDs) are gaining importance, both as urban innovation labs and as concrete, on-the-ground projects for creating future proof, energy-positive and climate-neutral urban living environments. Where do they come from and why should one have one or more PEDs developed in one’s own city?
Ahlers, Dirk, Alpagut, Beril, Cerna, Veronika, Cimini, Vincenzo, Haxhija, Sindi, Hukkalainen, Mari, Kuzmic, Michal, Livik, Klaus, Padilla, Marilisa, Poel, Marije, Sanz Montalvillo, Cecilia, Schouten, Socrates, Teigen Myrstad, Marit, van Wees, Mark, Williams, Karen, Wyckmans, Annemie, Gabaldon, Andrea, Fernandez Perez, Nora, Hirvonen Kantola, Sari, Dourlens, Sophie, Struiving, Els   +20 more
openaire   +2 more sources

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source