Results 71 to 80 of about 351,151 (266)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Global Dynamics and Bifurcations Analysis of a Two-Dimensional Discrete-Time Lotka-Volterra Model
Complexity, 2018 In this paper, global dynamics and bifurcations of a two-dimensional discrete-time Lotka-Volterra model have been studied in the closed first quadrant R2.
A. Q. Khan, M. N. Qureshi
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Global Asymptotic Behavior of yn+1=(pyn+yn−1)/(r+qyn+yn−1)
Advances in Difference Equations, 2008 We investigate the global stability character of the equilibrium points and the period-two solutions of yn+1=(pyn+yn−1)/(r+qyn+yn−1),n=0,1,…, with positive parameters and nonnegative initial conditions.
M. R. S. Kulenović, A. Brett
doaj +1 more source
Modeling the impact of host resistance on structured tick population dynamics
Mathematics in Applied Sciences and Engineering, 2020 For a variety of tick species, the resistance, behavioural and immunological response of hosts has been reported in the biological literature but its impact on tick population dynamics has not been mathematically formulated and analyzed using dynamical ...
Mahnaz Alavinejad +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Behavior of a Competitive System of Second-Order Difference Equations
The Scientific World Journal, 2014 We study the boundedness and persistence, existence, and uniqueness of positive equilibrium, local and global behavior of positive equilibrium point, and rate of convergence of positive solutions of the following system of rational difference equations ...
Q. Din, T. F. Ibrahim, K. A. Khan
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source