Results 141 to 150 of about 5,703 (300)
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
A study on sequential externality and the transmission mechanism
文献回顾表明,迄今为止关于外部性理论的研究都局限于静态分析,忽视了外部性动态传导问题。若由动态视角去分析外部性传导,则从中可以引出关于市场效率问题的极为重要的理论分析结论。本文提出了序贯外部性的概念,并对其动态传导和链式反应机制进行了探讨,构建了单向序贯外部性传导的数学模型,并剖析了双向序贯外部性传导的机理。文章指出,在外部性实施主体存在失当行为或利他行为进行转移私人成本时,市场的准入成本标准也随之发生了改变,其中正序贯外部性降低了外部性受体的准入成本标准,而负序贯外部性则提升了该标准 ...
林金忠, 董新龙
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ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Framing and cooperation in public good games: an experiment with an interior solution. [PDF]
We show that experimental subjects tend to contribute more to the public good if they perceive the actions of the others as a source of positive externality rather than a source of negative externality.
Marc WILLINGER, Anthony ZIEGELMEYER
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ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Entry and externality: Hydroelectric generators in Brazil
This paper analyzes the entry problem in the hydroelectric generation industry. The operation of an upstream generator regularizes the river flow for generators located downstream on the same river, increasing the production capacity of the latter.
Moita, Rodrigo M.S.
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Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source
Tourism and urban transport: Holding demand pressure under supply constraints [PDF]
Scholars and local planners are increasingly interested in tourism contribution to economic and social development. To this regard, several European cities lead the world rankings on tourist arrivals, and their governments have promoted tourism activity.
Daniel Albalate, Germà Bel
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Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source

