Results 171 to 180 of about 644,751 (309)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

On an approximation processes in the space of analytical functions

Open Mathematics, 2010
Gadjiev Akif, Ghorbanalizadeh Arash
doaj   +1 more source

Is Navigated Transcranial Magnetic Stimulation Capable of Detecting Different Motor Cell Clusters Within the Precentral Gyrus Using a Single Pulse Protocol? [PDF]

Brain Behav
Durner G, Colbus G, Marschal V, Sestito G, Kesseler HG, Sannwald L, Grübel N, Wirtz CR, Pala A, Becker R.   +9 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Identification of a novel monoclonal antibody derived from the lumpy skin disease virus ORF123 that confers cross-binding and cross-neutralizing activity against Capripoxvirus members. [PDF]

Vet Res
Ren S, Wang F, Gao X, Gao X, Rehman ZU, Zhang H, Wang X, Qiu X, Shang Y, Yin X, Wan X, Chen H, Sun Y.   +12 more
europepmc   +1 more source

Normal Positive Linear Mappings of Norm 1 from a von Neumann Algebra into Its Commutant and Its Application

, 1972
H. Araki
semanticscholar   +1 more source

Mixed linear model approach for mapping quantitative trait loci underlying crop seed traits

Heredity, 2014
Ting Qi, B. Jiang, Zhihong Zhu, Changshuai Wei, Y. Gao, Shuijin Zhu, Haiming Xu, Xiang-Yang Lou   +7 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Beyond Feature Selection: Interpretable Machine Learning for Mechanistic Insights in Metabolomics. [PDF]

Biology (Basel)
Bai H, Ren Y, Wang J, Wang Y, Yang Y.
europepmc   +1 more source

Holomorphic Fock spaces for positive linear transformations

, 2006
R. Fabec, G. Ólafsson, A. Sengupta
semanticscholar   +1 more source