Results 51 to 60 of about 24,734 (245)
Estimation of CARA Preferences and Positive Mathematical Programming
Open Journal of Statistics, 2018 The purpose of this paper is to combine the estimation of output price risk and positive mathematical programming (PMP). It reconciles the risk programming presented by Freund with a consistent estimate of the constant absolute risk aversion (CARA) coefficient.
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
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Can Thrifty Gene(s) or Predictive Fetal Programming for Thriftiness Lead to Obesity?
Journal of Obesity, 2011 Obesity and related disorders are thought to have their roots in metabolic “thriftiness” that evolved to combat periodic starvation. The association of low birth weight with obesity in later life caused a shift in the concept from thrifty gene to thrifty
Ulfat Baig +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Positive Mathematical Programming for Farm Planning: Review
Japan Agricultural Research Quarterly: JARQ, 2011 In the field of farm management and in related multidisciplinary fields such as bio-economic farm modeling and hydro-economic regional modeling, much attention has recently been paid to positive mathematical programming (PMP), primarily because of its ability to exactly reproduce an observed set of endogenous input variables in the model (e.g., an ...
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Arthritis Care &Research, Accepted Article.Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification. This study
Sung‐A Kim +2 more
wiley +1 more source
Flexible quota constraints in positive mathematical programming models
, 2008 Traditional deterministic programming models do not simulate any change of quota-limited decision variables as long as the quota have positive quota rents. However, in practice a quota constraint is rarely exactly binding because the decision variables are stochastic.
Buysse, Jeroen +5 more
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A scenario based project portfolio selection [PDF]
Management Science Letters, 2015 One of the primary assumptions in many project portfolio selection is the availability of all parameters. However, in real-world cases, many parameters are under uncertainty and the exact values are unknown in advance.
Kamran Pourahmadi +2 more
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A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source