Results 211 to 220 of about 2,413,015 (346)

Meditation and Positive Mental Health [PDF]

Journal of Psychiatry and Cognitive Behaviour, 2017
openaire   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Association between outdoor physical activity and positive mental health in adolescence: estimating the mediation effect of autonomy, competence and relatedness. [PDF]

Int J Behav Nutr Phys Act
Drapeau C, Lenze L, Montiel C, Gallant F, Bélanger M, Doré I.   +5 more
europepmc   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Positive Mental Health Screens in the Veterans Health Administration, 2021 to 2024.

JAMA Netw Open
Tran LD, Wagner TH, Bahraini N, Gujral K.   +3 more
europepmc   +1 more source

Psychological resources and illness recovery in later life: independent associations of positive mental health and attitudes to aging. [PDF]

BMC Geriatr
Wu J, Li Y, Chao Q.
europepmc   +1 more source

Positive practice in mental health [PDF]

British Dental Journal, 2005
openaire   +1 more source

An Exploration of the lived experience of sport and exercise for mental health service users - the journey to health

The aim of the study was to explore the lived experience of sport and exercise for mental health service users. There were three additional objectives; to investigate the effects of sport and exercise on mental health and wellbeing; to investigate the ...
Pickard, Luke
core  

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

From Military to Civilian Context: Adaptation of the SOCOM Spiritual Fitness Scale and Its Associations with Positive Mental Health and Depression in Poland. [PDF]

J Relig Health
Mamcarz P, Alexander D.
europepmc   +1 more source