Results 241 to 250 of about 2,413,015 (346)

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Core features of positive mental health in adolescents and their protective role against psychopathology. [PDF]

Sci Rep
Phua DY, Chew CSM.
europepmc   +1 more source

Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety‐Like Behaviors

Advanced Science, EarlyView.
ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Zhigang Chen, Xing Li
wiley   +1 more source

The effects of different types of leisure-time physical activity on positive mental health among adolescents: a mixed-methods systematic review and meta-analysis. [PDF]

Int J Behav Nutr Phys Act
Lenze L, Benzing V, Schmid J, Minder B, Henn RE, Frahsa A.   +5 more
europepmc   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Psychometric Properties and Gender Invariance of the Positive Mental Health Scale in Spanish Nurses During the COVID-19 Pandemic. [PDF]

Nurs Open
Robles-Bello MA, Sánchez-Teruel D, Boufellous S, Lendínez-Rodríguez C.   +3 more
europepmc   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Positive Mental Health Promotion - interventions developed through informatics applications: a scoping review

RevSALUS
Emanuel Pereira, Zaida Agüera, Carme Ferré-Grau, Teresa Lluch-Canut, Carlos Sequeira   +4 more
doaj   +1 more source

Levels of Hope, Stigma, Psychological Vulnerability, and Positive Mental Health: A Descriptive Study of Eighth- and Ninth-Grade Adolescents. [PDF]

Healthcare (Basel)
Nogueira MJC, Teixeira D.
europepmc   +1 more source

Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley, Sean Posey, Kathy Baylis, Daniel Osgood, Stuart Sweeney   +4 more
wiley   +1 more source