Results 221 to 230 of about 3,799,305 (383)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Positive predictive value of CD200 positivity in the differential diagnosis of chronic lymphocytic leukemia [PDF]

open access: bronze, 2019
Marc Sorigué   +7 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Part 2: Positive and negative predictive values of diagnostic tests

open access: yesEmergency, 2015
Saeed Safari   +3 more
doaj  

Determining the origin of genome aberrations improves the positive predictive value of NIPT for 22q11.2 deletion syndrome. [PDF]

open access: yesSci Rep
Xiang J   +13 more
europepmc   +1 more source

Titre-specific positive predictive value of antinuclear antibody patterns [PDF]

open access: bronze, 2019
Jean‐Baptiste Vulsteke   +8 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

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