Results 251 to 260 of about 3,799,305 (383)

23: Positive predictive value of low fetal fraction and atypical prenatal cfDNA screening results [PDF]

open access: diamond
Qiliang Ding   +7 more
openalex   +1 more source

Medicine's uncomfortable relationship with math: calculating positive predictive value.

open access: yesJAMA Internal Medicine, 2014
A. Manrai   +4 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

The positive predictive value of MOG-IgG testing based on the 2023 diagnostic criteria for MOGAD. [PDF]

open access: yesMult Scler J Exp Transl Clin
Nguyen L   +6 more
europepmc   +1 more source

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