Results 301 to 310 of about 4,110,990 (410)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Disseminated intravascular coagulation diagnosis: Positive predictive value of the ISTH score in a Danish population. [PDF]

Res Pract Thromb Haemost, 2021
Larsen JB, Aggerbeck MA, Granfeldt A, Schmidt M, Hvas AM, Adelborg K.   +5 more
europepmc   +1 more source

1038 Lesser Sensitivity and Positive Predictive Value of Fecal Immunochemical Test (FIT) in Right Advanced Colonic Neoplasia Than Left Lesions

, 2010
Hyunsoo Kim, Jong Won Byun, Chan Sik Won, Hoon Choi, So Yeon Park, Yong Hwan Kwon, Jae Woo Kim   +6 more
openalex   +1 more source

Response letter to T Fowler and co-authors – estimating the positive predictive value of opportunistic population testing for gonorrhoea as part of the English Chlamydia Screening Programme [PDF]

, 2014
Nigel Field, Gwenda Hughes, Iain T R Kennedy, C A Ison, Kevin Dunbar, André Charlett   +5 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Incorporation of second-tier tests and secondary biomarkers to improve positive predictive value (PPV) rate in newborn metabolic screening program. [PDF]

J Clin Lab Anal, 2022
Younesi S, Yazdani B, Taheri Amin MM, Saadati P, Jamali S, Modarresi MH, Savad S, Amidi S, Razavi H, Ghafouri-Fard S.   +9 more
europepmc   +1 more source

ALLERGIC DISEASES PRIMARY PREVENTION IN CHILDREN: POSITIVE PREDICTIVE VALUE AND HIGH SPECIFICITY OF INFORMATION ON ALLERGIC DISEASES IN MALE RELATIVES

, 2010
М С Тренева
openalex   +1 more source

Analysis of Sensitivity, Specificity, and Positive and Negative Predictive Values of Smear and Colposcopy in Diagnosis of Premalignant and Malignant Cervical Lesions [PDF]

, 2015
Mert Ulaş Barut, Ahmet Kale, Umur Kuyumcuoğlu, Murat Bozkurt, Elif Ağaçayak, Server Özekinci, Talip Gül   +6 more
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Positive predictive value and sensitivity of ICD-9-CM codes for identifying pediatric leukemia. [PDF]

Pediatr Blood Cancer, 2022
Weinmann S, Francisco MC, Kwan ML, Bowles EJA, Rahm AK, Greenlee RT, Stout NK, Pole JD, Kushi LH, Smith-Bindman R, Miglioretti DL.   +10 more
europepmc   +1 more source