Results 161 to 170 of about 2,193,779 (340)
Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation
Advanced Science, EarlyView.Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li +18 more
wiley +1 more source
Advanced Science, EarlyView.NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou +9 more
wiley +1 more source
Development the Body Appreciation Training Package and its Effectiveness on Worrying about Body Image and Overweight in Overweight Female High School Students in Isfahan [PDF]
Iranian Evolutionary Educational Psychology JournalObjective: The purpose of this investigation was to design a body appreciation training program (focusing on positive body image) and assess its impact on body image concerns and overweight among overweight adolescent girls in Isfahan. Methods: The study
Zahra Fathi, Yousef Gorgi
doaj
Advanced Science, EarlyView.This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang +6 more
wiley +1 more source
Wisdom, Chapter 1 of The Science of Virtue: Why Positive Psychology Matters to the Church
, 2017 The day before I started this chapter I played flag football with some of my doctoral students. Though I am thirty years their senior, I tried my best to keep up for three hours of great fun. Today my sore muscles scream any time I try to move.
McMinn, Mark R
core
A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness
Advanced Science, EarlyView.Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger +17 more
wiley +1 more source
Advanced Science, EarlyView.A cold atmospheric plasma‐activated in situ hydrogel (CAPgel/IL2) delivers reactive oxygen species and interleukin‐2 to modulate the hair follicle immune microenvironment, enhancing regulatory T‐cell expansion, dermal papilla cell proliferation, and the telogen‐to‐anagen transition for robust hair regeneration.
Jung Suk Kim +7 more
wiley +1 more source
Commentary: Primary Emotional Systems and Personality: An Evolutionary Perspective
Frontiers in Psychology, 2017 Stefano I. Di Domenico +2 more
doaj +1 more source