Results 51 to 60 of about 501,859 (300)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Understanding gender and age differences in language use: cross-cultural insights from Weibo and Facebook

Humanities & Social Sciences Communications
This study integrates social role theory and socioemotional selectivity theory to investigate the cultural universalities and differences in language use among male and female users across different age groups on Weibo and Facebook.
Dandan Pang, Sharath Chandra Guntuku, Garrick Sherman, Tingting Liu, Sunny Rai, Young-Min Cho, Rian You, Arnold B. Bakker, Lyle H. Ungar   +8 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

World Beliefs Predict Self-Reported Sustainable Behaviors Beyond Big Five Personality Traits and Political Ideology

Global Environmental Psychology
Generalized beliefs about the world—termed ‘primal world beliefs’ or ‘primals’—have been hypothesized to affect behavior, since they contain information which influences the perceived costs, benefits, and justifications for different behaviors.
Janna Hämpke, Nicholas Kerry, Jeremy D. W. Clifton   +2 more
doaj   +1 more source

Examining the Flourishing Impacts of Repeated Visits to a Virtual Art Museum and the Role of Immersion

Behavioral Sciences, 2022
Visiting art museums has been associated with a range of flourishing outcomes. However, there have been recent shifts towards increasing digital engagement with art, leading to a radical change in how people experience visual art. Given the now expansive
Katherine N. Cotter, Damien L. Crone, Rebekah M. Rodriguez-Boerwinkle, Martin Boerwinkle, Paul J. Silvia, James O. Pawelski   +5 more
doaj   +1 more source

Positive Psychology in Southern Europe (Greece, Italy, Portugal and Spain)

, 2022
This chapter illustrates the main applied research conducted in Southern Europe in the field of positive psychology. Even though this field is relatively new and underrepresented in this part of the world, by a theoretical viewpoint, the philosophical ...
Chiara Ruini
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Positive Attitude Upper Middle School social and emotional learning program: influences of implementation quality on program outcome

Frontiers in Psychology, 2023
IntroductionThere is an increased call for studies analyzing how implementation quality influences Social and Emotional Learning (SEL) program effectiveness.MethodsThe current dissemination study analyzed the effectiveness of the Positive Attitude Upper ...
Vítor Alexandre Coelho, Vítor Alexandre Coelho, Marta Marchante, Marta Marchante, Patrícia Brás   +4 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source