Results 201 to 210 of about 5,619,071 (301)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

A comparative analysis of Fagonia indica extracts and green synthesized nanoparticles for the determination of antioxidant potential. [PDF]

Sci Rep
Qureshi MS, Ghori FK, Idrees M, Zafar Z, Naseer F, Ahmed M.   +5 more
europepmc   +1 more source

Uniqueness of positive radial solutions of Δ𝑢+𝑓(𝑢)=0 in 𝑅ⁿ. II [PDF]

, 1993
Kevin McLeod
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Transglutaminase 2 in human peritoneal dialysis-related peritoneal injury. [PDF]

Physiol Rep
Kunoki S, Ikeno M, Tatsukawa H, Sakai Y, Kinashi H, Kamiya K, Suzuki M, Mizuno M, Yamaguchi M, Sasakura H, Morioka Y, Banshodani M, Tawada M, Iwabu M, Ishimoto T, Takeuchi K, Hitomi K, Kawanishi H, Ito Y.   +18 more
europepmc   +1 more source

Un résultat de non-existence de solution positive pour une équation elliptique [PDF]

, 1990
Xiaomin Zheng
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Structures, Interactions, and Antimicrobial Activity of the Shortest Thanatin Peptide from <i>Anasa tristis</i>. [PDF]

Int J Mol Sci
Abdullah SJ, Guan JS, Mu Y, Bhattacharjya S.   +3 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

On the solution for a nonlinear wave equation with variable exponent nonlinearity and a varying delay. [PDF]

Sci Rep
Benguessoum A, Bensaid M, Boulaaras S, Souid MS.   +3 more
europepmc   +1 more source