Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Existence of solutions to nonlocal elliptic problems with singular and combined nonlinearities
Jesus Alberto Leon Tordecilla
doaj
Evaluation of Six Commercial and Noncommercial Colistin Resistance Diagnostics. [PDF]
Leshaba TMS+3 more
europepmc +1 more source
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
The Automatable Activity-Based Approach to Complexity Unit Scoring as a task-specific model approach to monetizing outcomes of pathology artificial intelligence solutions. [PDF]
Pantelakos S, Nifora M, Agrogiannis G.
europepmc +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Monitoring the Antibacterial Activity of the Green Synthesized ZnO Nanoparticles on the Negative and Positive Gram Bacteria Mimicking Oral Environment by Using a Quartz Tuning Fork (QTF) Micromechanical Sensor. [PDF]
Al-Hamad KA+4 more
europepmc +1 more source
Positive superharmonic solutions to semi-linear elliptic eigenvalue problems
Ph. Clément, L. A. Peletier
openalex +1 more source
Positive solutions of binomial inequalities
openaire +3 more sources
Novel positioning solution for difficult tracheostomy
openaire +4 more sources