Novel positioning solution for difficult tracheostomy
openaire +3 more sources
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Evaluation of the neuroprotective potential of optimized intranasal polydopamine nanoparticles in a lipopolysaccharide-induced rat model for Alzheimer's disease management. [PDF]
Ibrahim RR +3 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Lab-in-a-cartridge for real-time detection of tuberculosis via precise measurement of urinary lipoarabinomannan. [PDF]
Heo W +9 more
europepmc +1 more source
Positive solutions of nonlinear integral equations and surjectivity of Non-Linear Markov Operators On Infinite Dimensional Simplex [PDF]
Farrukh Mukhamedov +2 more
openalex +1 more source
Existence of a positive solution to Kirchhoff type problems without compactness conditions
Yuhua Li, Fuyi Li, Junping Shi
semanticscholar +1 more source
Asymptotic behavior of global positive solution to a stochastic SIR model
D. Jiang, Jiajia Yu, Chunyan Ji, N. Shi
semanticscholar +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source

