Results 31 to 40 of about 2,146,074 (336)

On existence of positive periodic solutions [PDF]

open access: yesMonatshefte f�r Mathematik, 1998
We present the geometric method for detecting periodic solutions of time periodic nonautonomous differential equations in interior of convex subset of euclidean space. The method is based on the Lefschetz fixed point theorem and the topological principle of Wazewski. Two applications to the existence of positive periodic solutions are considered.
openaire   +1 more source

Positive solutions of Schrödinger-Kirchhoff-Poisson system without compact condition

open access: yesBoundary Value Problems, 2017
Purpose The existence of positive solutions for a class of nonlinear Schrödinger-Kirchhoff-Poisson systems. Methods Variational method. Results Some results on the existence of positive solutions.
Fengxia Liu, Shuli Wang
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Existence of positive solutions to a class of Caputo fractional differential equations

open access: yesJournal of Hebei University of Science and Technology, 2016
In order to investigate the existence of positive solutions to a class of Caputo fractional differential equation boundary value problems with p-Laplacian operator, the Green’s function is obtained by calculus, and its properties are discussed.
Yunhong LI, Wenjing LYU
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Study on the Algorithm of Multifunctional Bone External Fixator

open access: yesMATEC Web of Conferences, 2015
This paper discussed the problem that parameters of bone external fixator are difficult to calculate in the practical application. Positive solution is described in detail. We used MATLAB software to make simulation experiment.
Chen Jianwen   +3 more
doaj   +1 more source

Positive solutions for nonvariational Robin problems

open access: yesAsymptotic Analysis, 2018
We study a nonlinear Robin problem driven by the p-Laplacian and with a reaction term depending on the gradient (convection term). Using the theory of nonlinear operators of monotone-type and the asymptotic analysis of a suitable perturbation of the original equation, we show the existence of a positive smooth solution.
Papageorgiou, Nikolaos S.   +2 more
openaire   +5 more sources

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

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