Results 41 to 50 of about 1,891,065 (248)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Positive solutions for nonparametric anisotropic singular solutions

Opuscula Mathematica
We consider an elliptic equation driven by a nonlinear, nonhomogeneous differential operator with nonstandard growth. The reaction has the combined effects of a singular term and of a "superlinear" perturbation. There is no parameter in the problem. Using variational tools and truncation and comparison techniques, we show the existence of at least two ...
Nikolaos S. Papageorgiou, Vicen�iu D. R�dulescu, Xueying Sun   +2 more
openaire   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Sufficient conditions for the existence of non-oscillatory solutions to first-order differential equations with multiple advanced arguments

Electronic Journal of Differential Equations, 2018
This article concerns the existence of non-oscillatory solutions to the equation $$ x'(t)=\sum_{k=1}^m a_k(t) x(h_k(t)), $$ where $a_k\geq 0$ and $h_k(t)\geq t$. We generalize existing results and then give an answer to the open question stated in
Julio G. Dix
doaj  

Positive solutions of arbitrary order nonlinear fractional differential equations with advanced arguments [PDF]

Opuscula Mathematica, 2011
In this paper, we investigate the existence and uniqueness of positive solutions to arbitrary order nonlinear fractional differential equations with advanced arguments.
Sotiris K. Ntouyas, Guotao Wang, Lihong Zhang   +2 more
doaj   +1 more source

Positive Solutions for Nonlinear Eigenvalue Problems

Journal of Mathematical Analysis and Applications, 1997
The authors are concerned with determining values of \(\lambda\) (eigenvalues), for which there exist positive solutions of the boundary value problem \[ (1_\lambda)\quad u''+\lambda a(t)f(u)=0 ...
Henderson, Johnny, Wang, Haiyan
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Positive solutions for a nonlocal problem with singularity

Electronic Journal of Differential Equations, 2017
In this article we study a nonlocal problem involving singular nonlinearity. Based on the variational and perturbation methods, we obtain the existence of two positive solutions for this problem.
Chun-Yu Lei, Chang-Mu Chu, Hong-Min Suo
doaj  

The Existence and Representation of the Solutions to the System of Operator Equations A_iXB_i + C_iYD_i + E_iZF_i = G_i(i = 1, 2)

Axioms
In this paper, we give the necessary and sufficient conditions for the existence of general solutions, self-adjoint solutions, and positive solutions to the system of AiXBi+CiYDi+EiZFi=Gi(i=1,2) under additional conditions.
Gen Che, Guojun Hai, Jiarui Mei, Xiang Cao   +3 more
doaj   +1 more source