Results 61 to 70 of about 5,619,071 (301)

On the existence of positive solutions for certain difference equations and inequalities

open access: yesJournal of Inequalities and Applications, 1998
Some new results on the existence of positive solutions for certain difference equations and inequalities are established. The difference equations and inequalities considered are discrete analogues of some integrodifferential equations and inequalities.
Philos Ch G
doaj  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Steady-state solutions for Schrodinger equations in photonic lattice

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we study a nonlinear Schrodinger equation arising in optics. Firstly we prove the existence of multiple solutions of this equation. Secondly, we consider a nonlinear Schrodinger system which is intimately related to the Schrodinger ...
Wen-Long Li
doaj  

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

A Sub-Supersolution Approach for Robin Boundary Value Problems with Full Gradient Dependence

open access: yesMathematics, 2020
The paper investigates a nonlinear elliptic problem with a Robin boundary condition, which exhibits a convection term with full dependence on the solution and its gradient. A sub- supersolution approach is developed for this type of problems.
Dumitru Motreanu   +2 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Positive solutions for a class of elliptic equations

open access: yesComputers & Mathematics with Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yuying Zhou, Yisheng Huang
openaire   +2 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Sufficient conditions for the existence of non-oscillatory solutions to first-order differential equations with multiple advanced arguments

open access: yesElectronic Journal of Differential Equations, 2018
This article concerns the existence of non-oscillatory solutions to the equation $$ x'(t)=\sum_{k=1}^m a_k(t) x(h_k(t)), $$ where $a_k\geq 0$ and $h_k(t)\geq t$. We generalize existing results and then give an answer to the open question stated in
Julio G. Dix
doaj  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

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