Results 71 to 80 of about 5,619,071 (301)

Positive solutions of integro-differential inequalities

open access: yesComputers & Mathematics with Applications, 1997
In the present paper, the authors have studied the nonexistence of positive solutions of the following integrodifferential inequalities \[ (-1)^{n+ 1}y^{(n)}(t)+ \int^t_0 f(t- s,y(s))ds\leq 0 \] on \([0,\infty)\) \((n = 1,2,4)\) assuming that the inequalities \[ -\lambda^n+ \int^\infty_0 e^{\lambda^s} K(s)ds> 0,\quad\text{for all }\lambda>0\quad (n= 1 ...
Ravi P. Agarwal   +2 more
openaire   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Positive solutions for a nonlocal problem with singularity

open access: yesElectronic Journal of Differential Equations, 2017
In this article we study a nonlocal problem involving singular nonlinearity. Based on the variational and perturbation methods, we obtain the existence of two positive solutions for this problem.
Chun-Yu Lei, Chang-Mu Chu, Hong-Min Suo
doaj  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Bounded positive solutions of Schrödinger equations

open access: yesApplied Mathematics Letters, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhaoyang Yin, Zhaoyang Yin
openaire   +3 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Positive Solutions of Semilinear Equations in Cones [PDF]

open access: yesTransactions of the American Mathematical Society, 1992
In this paper we consider the problem of finding a positive solution of the equation Δ u + | x | ν u ( n + 2 + 2
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Positive periodic solutions for second-order neutral differential equations with functional delay

open access: yesElectronic Journal of Differential Equations, 2012
We use Krasnoselskii's fixed point theorem to prove the existence of positive periodic solutions of the second-order nonlinear neutral differential equation $$ frac{d^2}{dt^2}x(t)+p(t)frac{d}{dt}x(t)+q(t)x(t) =cfrac{d}{dt}x(t-au(t))+f(t,h(x(t)),g(x ...
Ernest Yankson
doaj  

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

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