Results 91 to 100 of about 15,510,191 (369)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Nonexistence of positive solutions for a nonpositone system in a ball

Electronic Journal of Differential Equations, 2015
In this article, we prove the nonexistence of positive solutions for a nonpositone system in a ball when the nonlinearities may have more than one zero.
Said Hakimi
doaj  

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Nonexistence of radial positive solutions for a nonpositone problem

Electronic Journal of Differential Equations, 2011
In this article we study the nonexistence of radial positive solutions for a nonpositone problem when the nonliearity is superlinear and has more than one zero.
Said Hakimi, Abderrahim Zertiti
doaj  

Existence results for a class of nonlinear singular p-Laplacian Hadamard fractional differential equations

Electronic Research Archive
Based on properties of Green's function and the some conditions of $ f(t, u) $, we found a minimal and a maximal positive solution by the method of sequence approximation.
Limin Guo, Weihua Wang , Cheng Li, Jingbo Zhao, Dandan Min   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Nature positive farm dams

Agricultural Water Management
Farm dams are a ubiquitous feature in agricultural landscapes worldwide, functioning as a major source of water for livestock or crop irrigation. Their number is increasing rapidly, often dominating the cumulative surface area of inland waters. Unmanaged
K.U.D.N. Hansani, Lukas Schuster, Peter I. Macreadie, Martino E. Malerba   +3 more
doaj  

Positive solutions for the one-dimensional Sturm-Liouville superlinear p-Laplacian problem

Electronic Journal of Differential Equations, 2018
We prove the existence of positive classical solutions for the p-Laplacian problem $$\displaylines{ -(r(t)\phi (u'))'=f(t,u),\quad t\in (0,1), \cr au(0)-b\phi ^{-1}(r(0))u'(0)=0,\ cu(1)+d\phi ^{-1}(r(1))u'(1)=0, }$$ where $\phi (s)=|s|^{p-2}s$, $p ...
Khanh Duc Chu, Dang Dinh Hai
doaj  

Periodic positive solutions of superlinear delay equations via topological degree. [PDF]

Philos Trans A Math Phys Eng Sci, 2021
Amster P, Benevieri P, Haddad J.
europepmc   +1 more source