Results 91 to 100 of about 3,840,200 (275)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Nonexistence of radial positive solutions for a nonpositone system in an annulus

open access: yesElectronic Journal of Differential Equations, 2011
In this article we study the nonexistence of radial positive solutions for a nonpositone system in an annulus by using energy analysis and comparison methods.
Said Hakimi
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Positive solutions and global bifurcation of strongly coupled elliptic systems

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we study the existence of positive solutions for the coupled elliptic system egin{gather*} -Delta u= lambda (f(u, v)+ h_{1}(x) ) quad ext{in }Omega, \ -Delta v= lambda (g(u, v)+ h_{2}(x))quad ext{in }Omega, \ u =v=0 quad ext{on ...
Jagmohan Tyagi
doaj  

Positive solutions of elliptic equations [PDF]

open access: yesPacific Journal of Mathematics, 1978
Moss, William F., Piepenbrink, John
openaire   +3 more sources

Positive Solutions of Quasilinear Elliptic Equations

open access: yesJournal of Mathematical Analysis and Applications, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Positive solutions of integrodifferential equations [PDF]

open access: yesInternational Journal of Stochastic Analysis, 1992
Integrodifferential equations of the forms urn:x-wiley:20903332:media:ista345783:ista345783-math-0001 are considered, where K ∈ C([0, ∞), [0, ∞)), p ∈ C([0, ∞), [0, ∞)) and q ∈ C((−∞, ∞), [0, ∞)). Necessary conditions and also sufficient conditions for the existence of positive solutions are established.
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Existence and iteration of monotone positive solutions for third-order nonlocal BVPs involving integral conditions

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
This paper is concerned with the existence of monotone positive solution for the following third-order nonlocal boundary value problem $u^{\prime \prime \prime }\left(t\right) +f\left( t,u\left( t\right), u^{\prime}\left( t\right)\right) =0 ...
Hai-E Zhang, Jian-Ping Sun
doaj   +1 more source

POSITIVE SOLUTIONS OF DIFFUSIVE LOGISTIC EQUATIONS

open access: yesTaiwanese Journal of Mathematics, 2001
The existence and uniqueness of positive solutions in the space \(C^{2+\theta}(\overline{D ...
openaire   +3 more sources

Home - About - Disclaimer - Privacy