Results 91 to 100 of about 3,840,200 (275)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Nonexistence of radial positive solutions for a nonpositone system in an annulus
In this article we study the nonexistence of radial positive solutions for a nonpositone system in an annulus by using energy analysis and comparison methods.
Said Hakimi
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Positive solutions and global bifurcation of strongly coupled elliptic systems
In this article, we study the existence of positive solutions for the coupled elliptic system egin{gather*} -Delta u= lambda (f(u, v)+ h_{1}(x) ) quad ext{in }Omega, \ -Delta v= lambda (g(u, v)+ h_{2}(x))quad ext{in }Omega, \ u =v=0 quad ext{on ...
Jagmohan Tyagi
doaj
Positive solutions of elliptic equations [PDF]
Moss, William F., Piepenbrink, John
openaire +3 more sources
Positive Solutions of Quasilinear Elliptic Equations
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Positive solutions of integrodifferential equations [PDF]
Integrodifferential equations of the forms urn:x-wiley:20903332:media:ista345783:ista345783-math-0001 are considered, where K ∈ C([0, ∞), [0, ∞)), p ∈ C([0, ∞), [0, ∞)) and q ∈ C((−∞, ∞), [0, ∞)). Necessary conditions and also sufficient conditions for the existence of positive solutions are established.
openaire +2 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This paper is concerned with the existence of monotone positive solution for the following third-order nonlocal boundary value problem $u^{\prime \prime \prime }\left(t\right) +f\left( t,u\left( t\right), u^{\prime}\left( t\right)\right) =0 ...
Hai-E Zhang, Jian-Ping Sun
doaj +1 more source
POSITIVE SOLUTIONS OF DIFFUSIVE LOGISTIC EQUATIONS
The existence and uniqueness of positive solutions in the space \(C^{2+\theta}(\overline{D ...
openaire +3 more sources

