Results 161 to 170 of about 15,510,191 (369)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Positive solutions of a boundary-value problem for second order ordinary differential equations

open access: yesElectronic Journal of Differential Equations, 2000
The existence of positive solutions of a two-point boundary value problem for a second order differential equation is investigated. By using indices of convergence of the nonlinearities at zero and at positive infinity, we providea priori upper and lower
George L. Karakostas, P. Ch Tsamatos
doaj  

A Solution of Indoor Positioning System

open access: yesProceedings of the 2013 International Conference on Advanced Computer Science and Electronics Information, 2013
This paper describes the use of ultra broadband indoor location technology within the area of the unified all personnel and equipment in planning, scheduling solution, realize the full view of the systematic monitoring sites, coherent continuous tracking and track the extraction.
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Stability properties of non-negative solutions of semilinear symmetric cooperative systems

open access: yesElectronic Journal of Differential Equations, 2004
We investigate the stability of non-negative stationary solutions of symmetric cooperative semilinear systems with some convex (resp. concave) nonlinearity condition, namely all second-order partial derivatives of each coordinate being non-negative (resp.
Imre Voros
doaj  

Nonuniformly elliptic equations: Positivity of weak solutions [PDF]

open access: gold, 1973
Charles V. Coffman   +2 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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