Results 211 to 220 of about 3,840,200 (275)

Institut Georges Lopez-2M as a Novel Lung Preservation Solution Attenuates Ischemia-Reperfusion Injury in a Rat <i>Ex Vivo</i> Lung Perfusion Model. [PDF]

Transpl Int
Barbarossa A, Van Slambrouck J, Trivett C, Kortleven P, Vanluyten C, Medina AM, Jin X, Jannis N, Özsoy B, Claes S, Schols D, Wylin T, Moermans K, Stegen S, Rosello AP, Inci I, De Leyn P, Vanaudenaerde B, Pirenne J, Jones EAV, Ceulemans LJ.   +20 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Correction: A lifestyle-based needs assessment of two European communities prior to the development and deployment of a digital health coaching smartphone application. [PDF]

Front Public Health
Iglesias-Cans M, Loughnane C, O'Donovan R, Iftimoaei C, Vasiliu D, Iftimoaei M, Enache I, Achitei A, Dunne PJ.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Weighted Aronson-Bénilan estimates and Harnack inequalities for slow diffusion equations with a nonlinear forcing term. [PDF]

Nonlinear Differ Equ Appl
Taheri A, Vahidifar V.
europepmc   +1 more source

Positioning solution in lunar mining

Today space mining is a one of most interesting investments which space agencies and private companies are dealing with. Space resources are excellent ore which can be used in space or be brought back to Earth. Application of new technologies and operational methodologies in terrestrial mining sector targets to obtain a beneficial outcome in a long ...
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Electrically Tunable Friction through Surface Adsorption Layer Restructuring. [PDF]

ACS Appl Mater Interfaces
Zhao Y, Zhu Z, Zhang J, Weiand E, Wang C, Ewen JP, Dini D, Spikes HA, Wong JSS.   +8 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Shoulder surgery preparation: a systematic review and meta-analysis. [PDF]

JSES Rev Rep Tech
Narulla RS, Ting R, Sima S, Diwan AD, Smith GCS.   +4 more
europepmc   +1 more source