Results 41 to 50 of about 2,932,216 (187)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Fractional Schrodinger-Poisson equations with general nonlinearities
Electronic Journal of Differential Equations, 2016 In this article we study the existence of positive solutions and ground state solutions for a class of fractional Schrodinger-Poisson equations in R^3 with general nonlinearity.
Ronaldo C. Duarte, Marco A. S. Souto
doaj
On a uniform estimate for positive solutions of semilinear elliptic equations [PDF]
, 2012 We consider semilinear elliptic equations with Dirichlet boundary conditions in a Lipschitz, possibly unbounded, domain. Under suitable assumptions on the nonlinearity, we deduce a condition on the size of the domain that implies the existence of a ...
Sourdis, Christos
core
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Positive Solutions of Advanced Differential Systems
The Scientific World Journal, 2013 We study asymptotic behavior of solutions of general advanced differential systems y˙(t)=F(t,yt), where F:Ω→ℝn is a continuous quasi-bounded functional which satisfies a local Lipschitz condition with respect to the second argument and Ω is a subset in ℝ×
Josef Diblík, Mária Kúdelčíková
doaj +1 more source
Positive solutions of a boundary value problem with integral boundary conditions [PDF]
, 2011 We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
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A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Bounded and large radially symmetric solutions for some (p,q)-Laplacian stationary systems
Electronic Journal of Differential Equations, 2012 This article concerns radially symmetric positive solutions of second-order quasilinear elliptic systems. In terms of the growth of the variable potential functions, we establish conditions such that the solutions are either bounded or blow up at ...
Adel Ben Dkhil, Noureddine Zeddini
doaj
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source