Results 91 to 100 of about 35,280,093 (311)

Positive solutions and global bifurcation of strongly coupled elliptic systems

Electronic Journal of Differential Equations, 2013
In this article, we study the existence of positive solutions for the coupled elliptic system egin{gather*} -Delta u= lambda (f(u, v)+ h_{1}(x) ) quad ext{in }Omega, \ -Delta v= lambda (g(u, v)+ h_{2}(x))quad ext{in }Omega, \ u =v=0 quad ext{on ...
Jagmohan Tyagi
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Multiple Positive Periodic Solutions for a Functional Difference System

Abstract and Applied Analysis, 2014
We obtain two existence results about multiple positive periodic solutions for a class of functional difference system. Two examples are given to illustrate our results.
Yue-Wen Cheng, Hui-Sheng Ding
doaj   +1 more source

On Metzler Positive Systems on Hypergraphs

IEEE Transactions on Control of Network Systems
In graph-theoretical terms, an edge in a graph connects two vertices while a hyperedge of a hypergraph connects any more than one vertices. If the hypergraph's hyperedges further connect the same number of vertices, it is said to be uniform. In algebraic graph theory, a graph can be characterized by an adjacency matrix, and similarly, a uniform ...
Shaoxuan Cui, Guofeng Zhang 0003, Hildeberto Jardón-Kojakhmetov, Ming Cao 0001   +3 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Existence of Positive Periodic Solutions for n-Dimensional Nonautonomous System

Discrete Dynamics in Nature and Society, 2014
In this paper we consider the existence, multiplicity, and nonexistence of positive periodic solutions for n-dimensional nonautonomous functional differential system x'(t)=H(t,x(t))-λB(t)F(x(t-τ(t))), where hi are ω-periodic in t and there exist ω ...
Youjun Liu, Huanhuan Zhao, Jurang Yan
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Investigating positive oxide charge in the SiO2/3C-SiC MOS system

AIP Advances, 2018
This paper investigates the origin of the fixed positive oxide charge often experimentally observed in Metal Oxide Semiconductor (MOS) structures of SiO2 formed on cubic silicon carbide (3C-SiC).
Karim Cherkaoui, Alan Blake, Yuri Y. Gomeniuk, Jun Lin, Brendan Sheehan, Mary White, Paul K. Hurley, Peter J. Ward   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source