Results 141 to 150 of about 500,195 (301)

Existence of global solutions for systems of reaction-diffusion equations on unbounded domains

Electronic Journal of Differential Equations, 2002
We consider, an initial-value problem for the thermal-diffusive combustion system $$displaylines{ u_t=aDelta u-uh(v) cr v_t=bDelta u+dDelta v+uh(v), }$$ where $a>0$, $d>0$, $beq 0$, $xin mathbb{R}^n$, $ngeq 1$, with $h(v)=v^m$, $m$ is an even nonnegative
Salah Badraoui
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Negatives about positivity and consistency as conditions for causal inference. [PDF]

Am J Epidemiol
Greenland S, Cole SR.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Temporal trends in pediatric group A streptococcal pharyngitis across the coronavirus disease 2019 era: A large retrospective cohort study. [PDF]

J Int Med Res
Nas Y, Gözüküçük S, Bayırlı H, Çakıroğlu B.   +3 more
europepmc   +1 more source

Colonies with position

Comput. Artif. Intell., 1996
Summary: A new type of grammar colony is introduced. Its individual components have some features of recognizing machines, nevertheless it is a generative system. The name `colonies with position' is proposed for it. The class \({\mathcal L}_{col_P (1)}\) of languages generated by a single component, as well as the class generated by colonies of such ...
openaire   +3 more sources

Is Body Positive really positive? Mixed methods research on the effectiveness of “Body Positivity” communication in self-perception

reserved#Bodypositive è realmente positivo? Ricerca con metodi misti sull’efficacia della comunicazione “Body Positivity” nella percezione del sé. Può il tag #bodypositive aiutare gli utenti dei social media, in particolare di Instagram, a percepire ...
FILICETTI, SARA
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Rare Case of CD68-Positive Congenital Granular Cell Epulis. [PDF]

Indian J Dermatol
Parida TK, Farween MS, Pati AB, Tamang M, Ayyanar P.   +4 more
europepmc   +1 more source

Extending the threshold values for inverse-positivity of a linear fourth order operator

, 2021
Janoušek, Jakub, Holubová, Gabriela
core   +1 more source