Results 121 to 130 of about 558,215 (330)

Experimental Determination of the Characteristics of a Positron Source Using Channeling

open access: yes, 2000
Numerical simulations and `proof of principle' experiments showed clearly the interest of using crystals as photon generators dedicated to intense positron sources for linear colliders.
Artru, X.   +31 more
core   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Collision Kinematics for Fast Positron Impact Ionization of Argon

open access: yesAtoms
Classical trajectory Monte Carlo calculations for 1 keV positron impact ionization of argon are presented. A combination of energy-weighted triple differential cross-sections is shown to provide good to excellent agreement compared with experimental data,
Robert D. DuBois, Károly Tőkési
doaj   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao   +14 more
wiley   +1 more source

Monte Carlo Code for Calculating the Elastic and Inelastic Scattering Cross Section Along with Mean Free Path of Positron Scattering in Kidney, Lung and Thyroid Organs

open access: yesEast European Journal of Physics
This research calculated the total cross sections for positron scattering in kidney, lung, and thyroid tissues along an energy range of 100 eV to 1 MeV.
Hawar M. Dlshad, Jamal M. Rashid
doaj   +1 more source

Learning Curve Effect in Reducing Local Recurrence Rate After Resection of Pancreatic Cancer With Arterial Abutment: A Single‐Center Retrospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida   +9 more
wiley   +1 more source

Conversion Therapy for cT4b and M1 Esophageal Squamous Cell Carcinoma: A Comprehensive Systematic Review

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We systematically reviewed conversion therapy for esophageal squamous cell carcinoma and propose a response‐based treatment strategy for cT4b and M1 disease. For cT4b, we emphasize definitive chemoradiotherapy with timed re‐evaluation and selective salvage or chemoselection to surgery; for M1, conversion is reserved for limited‐burden responders with ...
Eisuke Booka, Hiroya Takeuchi
wiley   +1 more source

Prevalence of 18F-fluorodeoxyglucose positron emission tomography abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy [PDF]

open access: green, 2018
Alexandros Protonotarios   +10 more
openalex   +1 more source

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee   +9 more
wiley   +1 more source

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