Results 31 to 40 of about 337,692 (304)

Development of an automated method for in-house production of sodium 18F-fluoride for injection: process validation as a step toward routine clinical application

EJNMMI Radiopharmacy and Chemistry
Background Sodium 18F-fluoride for injection can be easily cyclotron-produced and purified, as a simple inorganic salt, by adsorption/desorption onto an anion-exchange cartridge and then dispensed for clinical use.
Marija Atanasova Lazareva, Maja Chochevska, Katerina Kolevska, Maja Velickovska, Filip Jolevski, Paulina Apostolova, Ana Ugrinska, Emilija Janevik-Ivanovska   +7 more
doaj   +1 more source

Hypoxia Imaging in Lung Cancer: A PET-Based Narrative Review for Clinicians and Researchers

Pharmaceuticals
Background: Hypoxia plays a critical role in lung cancer progression and treatment resistance by contributing to aggressive tumor behavior and poor therapeutic response.
Ahmad Alenezi, Hamad Alhamad, Aishah Alenezi, Muhammad Umar Khan   +3 more
doaj   +1 more source

On the formation of trappable antihydrogen

New Journal of Physics, 2018
The formation of antihydrogen atoms from antiprotons injected into a positron plasma is simulated, focussing on the fraction that fulfil the conditions necessary for confinement of anti-atoms in a magnetic minimum trap.
S Jonsell, M Charlton
doaj   +1 more source

A Method to Measure Positron Beam Polarization Using Optically Polarized Atoms

Atoms, 2023
We outline an experimental technique for measuring the degree of polarization of a positron beam using an optically pumped, spin-polarized Rb target. The technique is based on the production and measurement of the ortho- and para-positronium fractions ...
Joshua R. Machacek, Sean Hodgman, Stephen Buckman, T. J. Gay   +3 more
doaj   +1 more source

Bayesian model comparison for compartmental models with applications in positron emission tomography [PDF]

, 2013
We develop strategies for Bayesian modelling as well as model comparison, averaging and selection for compartmental models with particular emphasis on those that occur in the analysis of positron emission tomography (PET) data.
Aston, John A. D., Zhou, Yan, Johansen, Adam M.   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

[11C]-L-Methionine positron emission tomography in the management of children and young adults with brain tumors [PDF]

, 2009
Only a few Methyl-[11C]-l-methionine (MET) positron emission tomography (PET) studies have focused on children and young adults with brain neoplasm. Due to radiation exposure, long scan acquisition time, and the need for sedation in young children MET ...
Johannes C. Klein, Frank Berthold, Kracht, L., Heiss, Wolf-Dieter, Herholz, Karl; id_orcid, Galldiks, N., Herholz, Karl, Klein, Johannes C., Heiss, Wolf Dieter, Jacobs, Andreas H., Hrvoje Miletic, Heiss, W., Lutz W. Kracht, Wolf-Dieter Heiss, Berthold, Frank, Klein, Johannes Christian, Jacobs, A., Kracht, Lutz W., Karl Herholz, Galldiks, Norbert, Miletic, Hrvoje, Herholz, K., Berthold, F., Norbert Galldiks, Klein, J., Kracht, Lutz Walter, Andreas H. Jacobs, Miletic, H.   +27 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The Jefferson Lab positron physics program

, 2023
International audienceThe Ce$^+$BAF project at the Thomas Jefferson National Accelerator Facility intends to develop over the coming years a high-duty cycle, high intensity, and high polarization positron beam to serve a unique Nuclear Physics ...
Voutier, Eric, Eric Voutier
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source