Results 121 to 130 of about 452,519 (325)

Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]

, 1995
Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core  

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Galactic diffuse gamma rays --- recalculation based on the new measurements of cosmic electron spectrum

, 2010
In this work, we revisit the all-sky Galactic diffuse $\gamma$-ray emission taking into account the new measurements of cosmic ray electron/positron spectrum by PAMELA, ATIC and Fermi, which show excesses of cosmic electrons/positrons beyond the expected
Aharonian, Barwick, Barwick, Bertone, Binns, Boezio, Borriello, Chappell, Connell, Coutu, Davis, Digel, Dobler, Duvernois, Einasto, Engelmann, Finkbeiner, Frail, Gralewicz, Hooper, Hu, Hunter, Juan Zhang, Kniffen, Li, Linden, Lu, Lukasiak, Mori, Moskalenko, Pavlov, Pohl, Porter, Porter, Profumo, Qiang Yuan, Sanuki, Sjöstrand, Sreekumar, Strong, Strong, Strong, Torii, Xiao-Jun Bi, Yuan   +44 more
core   +1 more source

Role of Post-Treatment 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients Receiving Definitive Chemoradiation for Locally Advanced Head and Neck Squamous Cell Carcinomas [PDF]

, 2022
Jae-Joon Kim, Sang-Bo Oh, Ki Sun Jung, Kwonoh Park, Seong‐Jang Kim, Yongkan Ki, Jin‐Choon Lee, So Yeon Oh   +7 more
openalex   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

Beam Induced Electron Cloud Resonances in Dipole Magnetic Fields

, 2016
The buildup of low energy electrons in an accelerator, known as electron cloud, can be severely detrimental to machine performance. Under certain beam conditions, the beam can become resonant with the cloud dynamics, accelerating the buildup of electrons.
Calvey, J. R., Hartung, W., Makita, J., Venturini, M.   +3 more
core   +2 more sources

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size

Pharmaceutics
Understanding the role of chemokine receptors in health and disease has been of increasing interest in recent years. Chemokine receptor CXCR4 has been extensively studied because of its defined role in immune cell trafficking, HIV infection, inflammatory
Isaline Renard, Thomas D’huys, Benjamin P. Burke, Trisha Ajoleza, Amy N. Cain, Neil L. Funwie, Abid Khan, Danny L. Maples, Randall D. Maples, Dallas L. Matz, Graeme McRobbie, Robert Ullom, Timothy J. Prior, Douglas P. Linder, Tom Van Loy, Timothy J. Hubin, Dominique Schols, Stephen J. Archibald   +17 more
doaj   +1 more source

Gamma-Rays from Positron Annihilation

, 2009
SPI on INTEGRAL has provided spectra and a map of the sky in the emission from annihilations of positrons in the interstellar medium of our Galaxy.
Diehl, Roland, Leising, Mark
core   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source