Results 111 to 120 of about 528,348 (385)

Detection rates of recurrent prostate cancer : 68Gallium (Ga)-labelled prostate-specific membrane antigen versus choline PET/CT scans. A systematic review [PDF]

, 2019
Background: The aim of this work was to assess the use of prostate-specific membrane antigen (PSMA)-labelled radiotracers in detecting the recurrence of prostate cancer.
Chaplin, Brian, KandaSwamy, Gokul Vignesh, Lane, Tim, Moghul, Masood, Peedell, Clive, Rai, Bhavan Prasad, Somani, Bhaskar, Vasdev, Nikhil   +7 more
core   +2 more sources

Ketone Body Infusion With 3‐Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background High levels of ketone bodies are associated with improved survival as observed with regular exercise, caloric restriction, and—most recently—treatment with sodium–glucose linked transporter 2 inhibitor antidiabetic drugs.
L. Gormsen, M. Svart, H. H. Thomsen, E. Søndergaard, M. Vendelbo, N. Christensen, L. Tolbod, H. Harms, R. Nielsen, H. Wiggers, N. Jessen, Jakob Hansen, H. Bøtker, N. Møller   +13 more
semanticscholar   +1 more source

CMOS‐Compatible Short‐Wave Infrared Linear Arrays of Ge‐on‐Si Avalanche Photodiodes

Advanced Photonics Research, EarlyView.
The fabrication and characterization of a new type of surface‐illuminated Si‐based avalanche photodiode array operating in the short‐wave infrared region using germanium as the absorber and silicon as the multiplier is reported. The demonstration of an avalanche gain of 24 at a temperature of 378 K allows the devices to operate in outdoor environments.
Mrudul Modak, Muhammad M. A. Mirza, Xin Yi, Qingyu Tian, Lisa Saalbach, Fiona Fleming, Jaroslaw Kirdoda, Derek C. S. Dumas, Xiao Jin, Charlie Smith, Levi Tegg, Sima Aminorroaya Yamini, John P. R. David, Douglas J. Paul, Ross W. Millar, Gerald S. Buller   +15 more
wiley   +1 more source

Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments. [PDF]

, 2012
PurposeAs imaging of the cell surface tetraspan protein epithelial membrane protein-2 (EMP2) expression in malignant tumors may provide important prognostic and predictive diagnostic information, the goal of this study is to determine if antibody ...
Braun, Jonathan, Brewer, Sarah, Fu, Maoyong, Gordon, Lynn K, Olafsen, Tove, Said, Jonathan, Wadehra, Madhuri, Wu, Anna M   +7 more
core   +3 more sources

Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography

Nature Network Boston, 2016
Tuberculosis is classically divided into states of latent infection and active disease. Using combined positron emission and computed tomography in 35 asymptomatic, antiretroviral-therapy-naive, HIV-1-infected adults with latent tuberculosis, we ...
H. Esmail, R. Lai, M. Lesosky, K. Wilkinson, C. Graham, A. Coussens, T. Oni, J. Warwick, Q. Said-Hartley, C. Koegelenberg, G. Walzl, J. Flynn, D. Young, Clifton E. Barry, III, A. O’Garra, R. Wilkinson   +15 more
semanticscholar   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

Advanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger   +6 more
wiley   +1 more source

Innovations in Instrumentation for Positron Emission Tomography.

Seminars in nuclear medicine, 2018
PET scanners are sophisticated and highly sensitive biomedical imaging devices that can produce highly quantitative images showing the 3-dimensional distribution of radiotracers inside the body.
E. Berg, S. Cherry
semanticscholar   +1 more source

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

Advanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao, Siming Chen, Anjin Wang, Ziyan Liang, Xuelian Liu, Yang Gao, Hongbing Cai   +6 more
wiley   +1 more source

Identifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography

Nature Communications, 2015
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and ...
Agnese Irkle, A. Vesey, David Y. Lewis, J. Skepper, Joseph L. E. Bird, M. Dweck, Francis R. Joshi, Ferdia A Gallagher, Elizabeth A. Warburton, Martin R. Bennett, Kevin M. Brindle, D. E. Newby, J. Rudd, Anthony P. Davenport   +13 more
semanticscholar   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source