Results 201 to 210 of about 377,076 (351)

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Towards P2X4 Positron Emission Tomography Tracing. [PDF]

J Med Chem
Federico S.
europepmc   +1 more source

Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography

, 1993
Alan J. Fischman, Eli Livni, John W. Babich, Nathaniel M. Alpert, Yuxi Liu, Edna Thom, Roy Cleeland, Barbara Prosser, John A. Correia, H. William Strausś   +9 more
openalex   +1 more source

Imaging atherosclerosis with positron emission tomography.

European Heart Journal, 2016
P. Joseph, A. Tawakol
semanticscholar   +1 more source

Prognostic role of high‐sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE‐CS

ESC Heart Failure, Volume 12, Issue 2, Page 869-878, April 2025.
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Yuichi Baba, Toru Kubo, Takeru Nabeta, Yuya Matsue, Takeshi Kitai, Yoshihisa Naruse, Tatsunori Taniguchi, Hidekazu Tanaka, Takahiro Okumura, Kenji Yoshioka, Hiroaki Kitaoka   +10 more
wiley   +1 more source

Explorations into Peptide Nucleic Acid Contrast Agents as Emerging Scaffolds for Breakthrough Solutions in Medical Imaging and Diagnosis

ACS Omega, 2021
Rüdiger M. Exner, Stephen J. Paisey, James E. Redman, Sofia I. Pascu   +3 more
doaj   +1 more source

Effect of reconstruction settings on radiomics feature robustness in positron emission tomography images: a clinical study. [PDF]

Quant Imaging Med Surg
Liu Y, Wang G, Yan X, Wang H, Li T, Yang S, Liu Z, Zhang S, Su X.   +8 more
europepmc   +1 more source

Positron Science and Its Application to Physical Measurements. VIII. Positron emission tomography. 4. Time-of-flight PET.

, 1993
Mikio Yamamoto
openalex   +2 more sources

Recent developments in positron emission tomography (PET) instrumentation [PDF]

, 1994

openalex   +1 more source

Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome

Circulation Cardiovascular Imaging, 2016
C. Rischpler, R. Dirschinger, S. Nekolla, H. Kossmann, Stefania Nicolosi, F. Hanus, S. van Marwick, K. Kunze, A. Meinicke, K. Götze, A. Kastrati, Nicolas Langwieser, T. Ibrahim, M. Nahrendorf, M. Schwaiger, K. Laugwitz   +15 more
semanticscholar   +1 more source