Results 281 to 290 of about 377,076 (351)

A Phase 1 Study of the Pharmacokinetics, Safety, and Tolerability of Posdinemab (JNJ‐63733657) in Healthy Chinese Adults

The Journal of Clinical Pharmacology, EarlyView.
Abstract Posdinemab, a humanized immunoglobulin G1/κ monoclonal antibody, binds with high affinity to phosphorylated tau protein which is associated with Alzheimer's disease (AD) pathophysiology. Posdinemab reduced tau seeding in murine models and was well tolerated in Phase‐1 clinical studies.
Fangfang Wang, Juanfang Liu, Daisy Bai, Lingjue Li, Maggie Fedgchin, David Henley, Haiyan Li, Fan Zhang   +7 more
wiley   +1 more source

A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies. [PDF]

Elife
Balligand T, Carpenet C, Olivé Palau S, Jaspers T, Suresh P, Liu X, Medhi H, Lee YH, Rashidian M, De Strooper B, Ploegh HL, Dewilde M.   +11 more
europepmc   +1 more source

Investigation Into the Utility of 3D Speckle‐Tracking Echocardiography in Detecting Coronary Artery Microcirculation Dysfunction in Ischemia With Non‐Obstructive Coronary Artery Disease

Journal of Clinical Ultrasound, EarlyView.
By detecting the subtle regional contractile dysfunction, 3D‐STE can efficiently distinguish CMCD and present a novel strategy for diagnosing INOCA. ABSTRACT Aim To assess the utility of three‐dimensional speckle‐tracking echocardiography (3D‐STE) in detecting coronary artery microcirculation dysfunction (CMCD) with non‐obstructive coronary artery ...
Yuexia Ma, Lina Guan, Xiaohong Li, Jianqiang Zhang, Xiaomei Li, Yuming Mu   +5 more
wiley   +1 more source

Emerging Applications of Positron Emission Tomography in Coronary Artery Disease. [PDF]

J Pers Med
Blach A, Kwiecinski J.
europepmc   +1 more source

The evolving role of positron emission tomography in precision prostate cancer biopsy. [PDF]

Eur J Clin Invest
Imperiale A, Berti V, Cazzato RL, Mamulashvili Bessac D, Ressault A, Vaggelli L, Helali M, Garcia C, Lang H, Deandreis D, Mertz L, Gangi A.   +11 more
europepmc   +1 more source

Comparison of Magnetic Resonance Spectra Acquired With Hybrid PET/MR and Standalone MR Scanners

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The effect of the positron emission tomography (PET) modality in hybrid PET/MR scanners on MR spectral quality is unclear. Purpose To evaluate spectral quality, quantification, and repeatability of brain MR spectroscopy (MRS) acquired on PET/MR and standalone MR scanners. Study Type Prospective.
Carter B. Macdonald, Aditya Bhattacharya, Benjamin B. Risk, Taylor M. Zuleger, Sagar Mandava, Ralph Noeske, Candace C. Fleischer   +6 more
wiley   +1 more source

Evaluation of [¹¹C]-Methionine Positron Emission Tomography and Cerebral Blood Volume Imaging in the Diagnosis of Non-Contrast-Enhanced Gliomas. [PDF]

J Clin Med
Imai N, Yano H, Ikegame Y, Yasuda S, Morishima R, Ikuta S, Nakayama N, Maruyama T, Ohe N, Kumagai M, Muragaki Y, Shinoda J, Izumo T.   +12 more
europepmc   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander, Tudor M. Ionescu, Mitul A. Mehta, Ottavia Dipasquale, Anouk Schrantee   +4 more
wiley   +1 more source

Advances in ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography for soft tissue sarcomas. [PDF]

World J Radiol
Zhu YL, Sun YW, Ge YC, He J, Li RT.
europepmc   +1 more source