Results 221 to 230 of about 2,211,422 (308)

Sporadic Hepatocellular Carcinoma in an Adolescent Harboring a Somatic CDH1 Mutation: A Case Report and Literature Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chang‐Wei Su, Peir‐In Liang, Shih‐Chang Chuang   +2 more
wiley   +1 more source

Neuromelanin‐Sensitive MRI as a Marker of Clinical Severity and Disease Burden in Parkinson's Disease: A Systematic Review and Meta‐analysis

Movement Disorders, EarlyView.
Abstract The neuropathology of Parkinson's disease (PD) is characterized in part by the degeneration of catecholaminergic neurons, particularly dopaminergic neurons in the substantia nigra pars compacta (SNpc) and noradrenergic neurons in the locus coeruleus (LC), yet no validated in vivo biomarker quantifies this process.
Rayo Akande, Thomas Kustermann, Štefan Holiga, Judith Anzures‐Cabrera, Patrik Brundin, Gennaro Pagano   +5 more
wiley   +1 more source

Microvascular dysfunction in patients with transthyretin cardiac amyloidosis evaluated by 13N-ammonia positron emission tomography-computed tomography: is it an early marker of the disease? [PDF]

Diagn Interv Radiol
Neto A, Cafezeiro C, Bueno B, Romero CE, Rosa VE, Hotta V, de Godoi Carneiro C, Rochitte C, Madrini V, Soares J, Chalela W, Lima M, Buchpiguel C, Miller E, Fernandes F.   +14 more
europepmc   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Prostate-specific membrane antigen immunostaining in endometriosis: preliminary findings and a case of in vivo imaging with gallium-68 positron emission tomography/computed tomography. [PDF]

BMC Womens Health
Martyna M, Łukasz K, Michał C, Kacper P, Magdalena B, Jolanta K.   +5 more
europepmc   +1 more source

QQ‐Based Oxygen Extraction Fraction (OEF) Mapping in Mouse Brain: Initial Experience

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Oxygen extraction fraction (OEF) is a vital biomarker of cerebral oxygen metabolism and tissue viability. A novel OEF mapping method, QQ, which combines quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent (qBOLD) (QSM + qBOLD = QQ), has demonstrated promise in detecting disease‐related OEF ...
Quinn Boyer, Dongkyu Lee, Tian Qiu, HyungJoon Cho, Junghun Cho   +4 more
wiley   +1 more source

Clinical Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT) in Suspected Spondylodiscitis: A Case Report. [PDF]

Cureus
Gutierrez Albenda D, Balmaceda Araya E, Armani Arce V, Osawa Pivovarov A, Montoya Porras Á.   +4 more
europepmc   +1 more source

Serum elemental profile‐based machine learning models for Alzheimer's disease identification and cognitive score prediction

Neuroprotection, EarlyView.
Serum elemental profiling combined with machine learning supports exploratory Alzheimer's disease (AD) identification and cognitive score prediction. In this retrospective cross‐sectional study, 874 participants from the BANC‐PUMC, including cognitively normal controls and patients with AD, were analyzed.
Haotian Liu, Xinnan Liu, Yashuang Chen, Meng Pan, Ying Fu, Chao Ma, Wei Ge   +6 more
wiley   +1 more source

TNM-Accountable Whole-Body 3-Dimensional Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Report Drafting in Lung Cancer Cohorts via Structured Impressions and Organ-wise Exemplar Synthesis. [PDF]

Research (Wash D C)
Wang H, Xie X, Liu E, Gao Y, Wu X, Cong S, Han J, Zhang N, Zheng H, Liang D, Yao X, Jiang L, Hu Z.   +12 more
europepmc   +1 more source

Radiation Shielding Performance of B4C‐Reinforced Ultra‐High Molecular Weight Polyethylene Composites Against Low‐Energy X‐Rays: Experimental and Computational Analysis

Polymer Composites, EarlyView.
Radiation shielding behavior of B4C‐reinforced UHMWPE composites. ABSTRACT The present study investigates the radiation shielding performance of ultra‐high molecular weight polyethylene (UHMWPE) composites reinforced with varying boron carbide (B4C) contents against low‐energy X‐rays through combined experimental and computational approaches.
Elif Altındaş, Yalçın Kalkan, Gozde Celebi Efe, Aysun Ayday, Tuba Yener   +4 more
wiley   +1 more source