Results 91 to 100 of about 5,040,967 (335)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Quantum Information Dynamics and Open World Science [PDF]
, 2007 One of the fundamental insights of quantum mechanics is that complete knowledge of the state of a quantum system is not possible. Such incomplete knowledge of a physical system is the norm rather than the exception. This is becoming increasingly apparent
Bruza, Peter, Widdows, Dominic
core +1 more source
A Bio-Logical Theory of Animal Learning [PDF]
, 2009 This article provides the foundation for a new predictive theory of animal learning that is based upon a simple logical model. The knowledge of experimental subjects at a given time is described using logical equations.
A Blaisdell +32 more
core +2 more sources
Set Theory, Topology, and the Possibility of Junky Worlds [PDF]
Notre Dame Journal of Formal Logic, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Will Mathematics Ultimately Describe Nature? [PDF]
Философия и космология, 2019 It has been almost eighty years since Paul Dirac delivered a lecture on the relationship between mathematics and physics and since 1960 that Eugene Wigner wrote about the unreasonable effectiveness of mathematics in the natural sciences.
James R. Johnson
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Fixing an ambiguity in two dimensional string theory using string field theory
Journal of High Energy Physics, 2020 In a recent paper, Balthazar, Rodriguez and Yin found some remarkable agreement between the results of c = 1 matrix model and D-instanton corrections in two dimensional string theory.
Ashoke Sen
doaj +1 more source
Leibniz, Acosmism, and Incompossibility [PDF]
, 2016 Leibniz claims that God acts in the best possible way, and that this includes creating exactly one world. But worlds are aggregates, and aggregates have a low degree of reality or metaphysical perfection, perhaps none at all.
C Wilson +22 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source