Results 171 to 180 of about 5,040,967 (335)
Phenomenon-oriented lifeworld-led data generation in qualitative research-challenging absent or inadequate choices of methods. [PDF]
Dahlberg H +3 more
europepmc +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
The marginal majority effect: When social influence produces lock-in. [PDF]
Gelastopoulos A +3 more
europepmc +1 more source
Equilibrium - Scaling possible worlds "theory of necessity Btath"
«نظریه ضرورت بتّاته» عنوان نظریهای است از «شیخ شهاب الدین سهروردی» که از ابداعات و نوآوریهای مهم وی در عرصه منطق تلقی میشود و دارای نتایج منطقی – فلسفی فراوانی است. سهروردی بدون تردید با طرح این نظریه به «ضرورت فلسفی – متافیزیکی» نظر داشته و از آنجا که تبیین منطقی ضرورت فلسفی از دغدغههای مهم چند دهه اخیر در حوزه منطق موجهات جدید بوده است، بررسی ...
openaire +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The experimental psychology behind coordination. [PDF]
Padovani F.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source

