Results 241 to 250 of about 12,774,178 (324)

Editorial: Novel sociological methods and practices of engagement across disability communities. [PDF]

Front Sociol
Landry D, Middelmann T, Abay R, Morgan H, Soldatić K.   +4 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Tukdam, Different Ontological Bodies, and Making Tibetan Deaths Visible. [PDF]

Cult Med Psychiatry
Coleman D.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Thermodynamic Constraints on the Citric Acid Cycle and Related Reactions in Ocean World Interiors. [PDF]

ACS Earth Space Chem
Işık S, Melwani Daswani M, Işık E, Weber JM, Olgun Kıyak N.   +4 more
europepmc   +1 more source

An ecological model of vaginal dysbiosis provides new research leads. [PDF]

PLoS Biol
Massol F.
europepmc   +1 more source

The role of satisfaction with the way you look in 10 to 12-year-olds' health and subjective well-being across genders and cultures. [PDF]

Sci Rep
González-Carrasco M, Casas F, Malo S, Oriol X, Cámara D.   +4 more
europepmc   +1 more source

Dino's Story: The Challenges of Co-writing the Life History of a Brazilian Gangster. [PDF]

Crit Criminol
Cohen C.
europepmc   +1 more source

Core metamorphism controls the dynamic habitability of mid-sized ocean worlds-The case of Ceres. [PDF]

Sci Adv
Courville SW, Castillo-Rogez JC, Daswani MM, Robare J, O'Rourke JG.   +4 more
europepmc   +1 more source

Reducing Heavy Drinking Through the "Sober Curious" Movement in Australia: Protocol for a Mixed Methods Study.

JMIR Res Protoc
Ward PR, Savic M, MacLean S, Lunnay B, Lyons A, Hughes T, London K, Caluzzi G, Pettigrew S, Pennay A, Meyer S, Duncan T, Lee N.   +12 more
europepmc   +1 more source