Results 81 to 90 of about 217,406 (169)
Advanced Science, EarlyView.An acoustic‐responsive therapeutic platform for synergistic sonopiezoelectric‐gaseous osteosarcoma therapy and bone regeneration is fabricated through the joint loading of few‐layer black phosphorus nanosheets and S‐Nitroso‐L‐glutathione onto the 3D‐printed bioactive glass scaffolds.
Haoyu Fang +8 more
wiley +1 more source
Advanced Science, EarlyView.In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang +10 more
wiley +1 more source
Advanced Science, EarlyView.A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu +9 more
wiley +1 more source
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
A Neutral and Stable Macrocyclic Mn(II) Complex for MRI Tumor Visualization
ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022 Research on contrast agents for magnetic resonance imaging has recently guided efforts toward paramagnetic Mn(II) and Fe(III) complexes as alternatives to the well‐established Gd(III)‐based agents regularly used in clinical settings.The new neutral Mn(II) complex MnDO2AMGly reported herein shows good relaxometric performance, no toxicity, and in vivo ...
Loredana Leone +5 more
wiley +1 more source
Advanced Science, EarlyView.Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi +11 more
wiley +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
Advanced Science, EarlyView.In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li +6 more
wiley +1 more source
Advanced Science, EarlyView.A simple and effective non‐solvent‐induced microstructure rearrangement (MSR) technique is proposed to enhance the gas separation performance of Pebax 2533 membranes. By immersing Pebax 2533 membranes in amino acid salt solutions to induce MSR, the CO2 permeability of the Pebax 2533‐GlyK 10 wt.% membrane reached 1180 Barrer.
Jing Wei +16 more
wiley +1 more source
EcoMat, Volume 5, Issue 1, January 2023., 2023 Non‐fullerene organic solar cells (NFA‐OSCs) have seen massive progress in power conversion efficiencies surpassing 19%, benefiting from material innovation and device engineering. Moreover, NFA‐OSCs show great potential for promising applications, such as semitransparent and flexible photovoltaic technology. This review outlines the latest progress of
Ying Zhang, Yongwen Lang, Gang Li
wiley +1 more source