Results 81 to 90 of about 35,620 (147)

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

Advanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong, Wenxiao Shi, Xingzhu Liu, Hang Yu, Yinghui Wu, Yanzhang Xia, Caichun Yue, Chongkai Yang, Cong Shen, Renjun Pei, Tianwen Xin, Hailong Pei, Jun Shen   +12 more
wiley   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Advanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng, Shuting Zheng, Yushu Liao, Zede Wu, Chenxi He, Qiuyu Li, Honglei Hu, Zheyu Shen, Yikai Xu, Chenggong Yan, Bingxia Zhao, Meirong Hou   +11 more
wiley   +1 more source

Microstructural Origin of Nonmonotonic Piezoresistivity in Polymer Nanocomposites

Advanced Science, EarlyView.
When polymer nanocomposites are subjected to tensile loading, the electrical resistance‐strain relationship may be nonmonotonic, hampering the use of these materials in real‐world applications. This challenge is addressed through the collaborative use of physical experimentation and computer simulations, establishing the inter‐nanotube junction ...
Ting Yui Wong, Kui Lin, Tao Yu, Fangxin Zou   +3 more
wiley   +1 more source

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

Advanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li, Bo Ma, Jia‐Wei Lu, Kai‐Chao Zhang, Chao Ma, Sheng‐Feng Bai, Yan‐Jiao Li, Si‐Qi Ying, Wei‐Zong Weng, Kai Zhang, Xi‐Wang Hu, Rang Li, Chen‐Xi Zheng, Xiao‐Ru Xu, Ji Chen, Fang Jin, Hao‐Kun Xu, Jian‐Wei Xie, Yan Jin, Yi Shuai, Bing‐Dong Sui   +20 more
wiley   +1 more source

Transparent and Transient Flexible Electronics

Advanced Science, EarlyView.
Transparent electronics has gained tremendous attention in recent years because of the growing demand for see‐through devices in applications such as displays, windscreens, and wearables. This review discusses the recent developments related to transparent electronics as well as the challenges associated with the development of flexible and transient ...
Nitheesh M. Nair, Ayoub Zumeit, Ravinder Dahiya   +2 more
wiley   +1 more source

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

Advanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou, Mengjie Hou, Baoshuai Bai, Yiwu Zhang, Yiwei Shen, Zenghui Jia, Yongqiang Guo, Guangdong Zhou, Xiaoqin Liang   +8 more
wiley   +1 more source

Optimized Synthesis and Characterization of Janus RhSeCl with Uniform Anionic Valences, Nonlinear Optical and Optoelectronic Properties

Advanced Science, EarlyView.
Janus RhSeCl exhibits a facial heteroatom configuration and uniform anionic valences with Se and Cl in the −1 oxidation state, stabilizing the unique structure. The symmetry‐breaking nature enables promising nonlinear optical and optoelectronic performance, providing new insights into two–dimensional (2D) Janus materials and broadening their potential ...
Kefeng Liu, Xuelian Sun, Puxin Cheng, Zhiteng Li, Penghui Li, Donghan Jia, Shijing Zhao, Xin Yang, Xinyu Wang, Liangting Ye, Shengqing Xia, Shuo Zhang, Yu Chen, Tao Gan, Jiong Li, Xiao Zhang, Jialiang Xu, Anmin Nie, Bing Huang, Huiyang Gou   +19 more
wiley   +1 more source

Flame‐Retardant Ionogel Enabled by Lignin Molecular Networks for Fire Rescue

Advanced Science, EarlyView.
Wearable sensors for harsh, high‐temperature, fire‐prone environments face challenges in heat resistance and stability. This study introduces a flame‐retardant, waterproof glycol lignin ionogel (GLI) with a robust 3D network, exceptional tensile strength, strong adhesion, biocompatibility, eco‐safety, and dual temperature‐motion sensing, even after ...
Zewei Ye, Haomeng Yu, Hongxia Xie, Wenwen Zhu, Shitao Shi, Chencong Liu, Yuanyuan Wang, Jiaqi Liao, Qingfeng Sun, Dawei Zhao, Xiaoping Shen   +10 more
wiley   +1 more source

Layer‐By‐Layer Approach to Improve the Capacitance of Conducting Polymer Films

Advanced Electronic Materials, EarlyView.
This work describes the synthesis and characterization of a composite material based on poly(3,4‐ethylenedioxythiophene) (PEDOT) and poly(3,4‐ethylenedioxypyrrole) (PEDOP) deposited in a layer‐by‐layer approach. Due to the developed electroactive area coming from the presence of 3D nanostructures, PEDOT/PEDOP demonstrates superior areal capacitance ...
Małgorzata Skorupa, Ethan Cao, Adrian Barylski, Sara Shakibania, Sandra Pluczyk‐Małek, Zuzanna Siwy, Katarzyna Krukiewicz   +6 more
wiley   +1 more source

Highly Efficient Spin‐Orbit Torque Switching in a Topological Insulator/Chromium Telluride Heterostructure with Opposite Berry Curvature

Advanced Electronic Materials, EarlyView.
This study reports high spin‐torque efficiency (ΔHLJ=12.9×10−6mTA−1cm2$\frac{{{{\Delta}}{H_L}}}{J} = 12.9 \times {10^{ - 6}}{\mathrm{mT}}\;{{\mathrm{A}}^{ - 1}}{\mathrm{c}}{{\mathrm{m}}^2}$) and spin Hall conductivity (σSH=4.8×106ℏ2eΩ−1m−1${\sigma _{SH}} = 4.8 \times {10^6}\frac{\hbar }{{2e}}{{{\Omega}}^{ - 1}}{{\mathrm{m}}^{ - 1}}$), along with ...
Kewen Zhang, Yuhang Wu, Jingyan Song, Yitian Guo, Xiaolun Cai, Long Cheng, Dongxing Zheng, Aitian Chen, Peng Li, Xixiang Zhang   +9 more
wiley   +1 more source