Results 181 to 190 of about 36,243,698 (226)

Post-marketing study design to evaluate the effectiveness of the 9-valent and 4-valent HPV vaccines on serious HPV-related cervical disease in China. [PDF]

Hum Vaccin Immunother
Yang Y, Zhang L, Hartwig S, Jiang P, Zhao H, Meng R, Liu Z, Liu Z, Ding K, You X, Koro C, Xu G, Zhan S.   +12 more
europepmc   +1 more source

Solvent/Detergent-Treated Plasma in the Management of Pediatric Patients Who Require Replacement of Multiple Coagulation Factors: An Open-Label, Multicenter, Post-marketing Study. [PDF]

Front Pediatr, 2020
Spinella PC, Borasino S, Alten J.
europepmc   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

A post-marketing study to evaluate the safety and immunogenicity of a quadrivalent influenza split-virion vaccine in elderly people aged 60 years and older. [PDF]

Trop Dis Travel Med Vaccines
Kou Z, Li X, Liu T, Fan B, An W, An W, Dang M, Zhang K, Tang J, Zhu N, Pan R.   +10 more
europepmc   +1 more source

Safety and effectiveness of tofogliflozin in elderly Japanese patients with type 2 diabetes mellitus: A subanalysis of a post-marketing study (J-STEP/EL Study). [PDF]

J Diabetes Investig, 2020
Kaku K, Naito Y, Senda M, Kurihara Y, Gunji R, Kakiuchi S, Utsunomiya K.   +6 more
europepmc   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Safety and Effectiveness of Dulaglutide in the Treatment of Type 2 Diabetes Mellitus: A Korean Real-World Post-Marketing Study. [PDF]

Diabetes Metab J
Han J, Lee WJ, Hur KY, Cho JH, Lee BW, Park CY.   +5 more
europepmc   +1 more source

Design of a non-interventional post-marketing study to assess the long-term safety and effectiveness of ocrelizumab in German real world multiple sclerosis cohorts - the CONFIDENCE study protocol. [PDF]

BMC Neurol, 2020
Dirks P, Zingler V, Leemhuis J, Berthold H, Hieke-Schulz S, Wormser D, Ziemssen T.   +6 more
europepmc   +1 more source

Pt‐Regulated Dynamic Cu(0) Regeneration in CuPt Alloy Enables High‐Efficiency Self‐Driven Formaldehyde Fuel Cells for Potassium Formate Production

Advanced Science, EarlyView.
In this work, a Cu30PtX/CF anode material was synthesized to effectively catalyze the electrocatalytic formaldehyde oxidation, and thereby assembled a fuel cell that offered a high open‐circuit potential of 0.94 V and a power density of 34.3 mW cm−2. This work realizes the co‐generation of electrical energy and high‐value‐added chemicals with nearly ...
Hanxu Hou, Yan Zhou, Weixiang Tang, Desheng Sui, Siman Tao, Xiaohan Li, Hui Zhang, Jiawei Qiang, Wenle Li, Jun Zhang   +9 more
wiley   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source