Results 221 to 230 of about 251,219 (284)

PLGA‐particle‐based vaccine induces SARS‐CoV‐2‐specific antibody and T‐cell responses

open access: yesBritish Journal of Pharmacology, EarlyView.
A novel coronavirus disease 2019 (COVID‐19) vaccine encapsulating recombinant severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike receptor binding domain (RBD) with the double stranded RNA (dsRNA) analogue Riboxxim induces robust systemic and respiratory T‐ and B‐cell responses in mice.
Dennis Horvath   +6 more
wiley   +1 more source

Drivers of bat researchers’ intent to adopt field hygiene practices

open access: yesConservation Biology, EarlyView.
Abstract Infectious disease is a growing threat to wildlife, with zoonotic transmission most likely at the human–wildlife interface. One underappreciated activity at this interface is fieldwork with wild animals, but associated risks can be mitigated through field hygiene (FH) practices, such as using personal protective equipment and other appropriate
Joanna L. Coleman   +6 more
wiley   +1 more source

Testing the feasibility of an intermittent low‐energy diet in women with gestational diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The study aimed to assess feasibility, acceptability and safety of an ILED in a randomised controlled trial of ILED vs. best NHS care healthy diet and exercise advice in women with Gestational Diabetes Mellitus (GDM) with body mass index ≥27.5 kg/m2 (≥25 kg/m2 in high‐risk minority ethnic groups) in the last trimester of pregnancy ...
Elizabeth Dapre   +11 more
wiley   +1 more source

In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Type 1 diabetes (T1D) is an autoimmune disease, but knowledge of immune cell infiltration in the human pancreas is limited due to the risks associated with pancreatic biopsies. This study aimed to evaluate the feasibility of imaging innate immune cells in vivo using positron emission tomography (PET).
Ebrahim Anvari   +9 more
wiley   +1 more source

Effects of post-acute COVID-19 syndrome on cerebral white matter and emotional health among non-hospitalized individuals. [PDF]

open access: yesFront Neurol
Churchill NW   +12 more
europepmc   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

open access: yesThe FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl   +11 more
wiley   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Investigating Symptom Duration Using Current Status Data: A Case Study of Postacute COVID-19 Syndrome. [PDF]

open access: yesEpidemiology
Wolock CJ   +11 more
europepmc   +1 more source

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