Results 141 to 150 of about 5,184,324 (291)

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

Colonial Experience and Postcolonial Underdevelopment in Africa [PDF]

open access: yes
IIn this paper, we analyze the connection between the history of colonial rule and postcolonial development in Africa. We focus on the fact that many African colonies were governed by indirect rule. Under indirect rule, indigenous people are divided into
Ryosuke Okazawa, Nobuhiro Mizuno
core  

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

Clustering of 770,000 genomes reveals post-colonial population structure of North America. [PDF]

open access: yesNat Commun, 2017
Han E   +18 more
europepmc   +1 more source

Report of Local Committee [on] Queensland : remarks / by Colonial Defence Committee.

open access: yes, 1890
Caption title.; At head of title: Confidential. Queensland 25001.; "Printed for the use of the Colonial Office. March 4, 1890."; Electronic reproduction. Canberra, A.C.T.
Great Britain. Colonial Defence Committee.
core  

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy