Results 221 to 230 of about 5,184,324 (291)

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Saskia Cousin Kouton. 2024. Ògún et les matrimoines : Histoires de Porto-Novo, Xògbónù, Àjàse

Culture & Musées
Jean-Louis Fabiani
doaj   +1 more source

From Portuguese Colonial Representations to Racist Endorsement: Investigating Correlational and Causal Paths. [PDF]

Int Rev Soc Psychol
Meuer F, Guerra R, Madeira F, Valentim JP.   +3 more
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

Beyond geopolitics: Greenland's suicide crisis. [PDF]

Lancet Reg Health Eur
The Lancet Regional Health-Europe.
europepmc   +1 more source

Introduction to the special issue: Global South histories of madness - new perspectives on mental troubles and psychiatry from Latin America and Africa in the 19th and 20th centuries. [PDF]

Med Hist
Favier I, Tiquet R.
europepmc   +1 more source

Southwestern Arabia through the eyes of Western orientalists during the first half of the twentieth century. [PDF]

Front Sociol
Saigh IAI.
europepmc   +1 more source

Whole-body regeneration and polarity repatterning in polyps of <i>Xenia umbellata</i> (Octocorallia). [PDF]

PeerJ
Nadir E, Marillac V, Lotan T, Benayahu Y.   +3 more
europepmc   +1 more source

Nursing the colonised: the politics of representation of the Western nurse in plague-stricken Bombay. [PDF]

Med Hist
Koshy R.
europepmc   +1 more source