Results 171 to 180 of about 6,651,279 (337)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Health-care worker retention in post-conflict settings: a systematic literature review. [PDF]
Health Policy Plan, 2023 Lin TK, Werner K, Kak M, Herbst CH.
europepmc +1 more source
From Predation to Production Post-conflict [PDF]
This paper builds an analytical framework that models predation (banditry) and production as part of the choice of a rational utility-maximising agent. Aggregating this choice up for society produces equilibrium outcomes ranging from Utopia (where no one
Satish Chand
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
El Ágora USB, 2015 Este artículo presenta una caracterización de las instancias comunitarias de resolución de conflictos que desde hace más de una década son las encargadas de tramitar conflictos en la región de la Sierra de La Macarena, Colombia.
Nicolás Espinosa Menéndez
doaj
The role of community health worker-based care in post-conflict settings: a systematic review. [PDF]
Health Policy Plan, 2023 Werner K, Kak M, Herbst CH, Lin TK.
europepmc +1 more source
Sustainability of post-disaster and post-conflict sheltering in Africa: What matters?
Sustainable Production and Consumption, 2019 Francesco Pomponi +4 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Piloting a mental health intervention for young adults in poverty enrolled in post-secondary education in post-conflict regions in Colombia: a study protocol. [PDF]
Front Psychiatry, 2023 Zimmerman A +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source