Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Post-emergence seedling damage due to vertebrate pests and its impact on soybean establishment. [PDF]
PeerJ, 2021 Lamichhane JR.
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Aedes aegypti post-emergence transcriptome: Unveiling the molecular basis for the hematophagic and gonotrophic capacitation. [PDF]
PLoS Negl Trop Dis, 2021 de Carvalho SS +15 more
europepmc +1 more source
Emergency and post-emergency situations Educational and teaching model
Ricerche di Pedagogia e Didattica, 2013 Ricerche di Pedagogia e Didattica. Journal of Theories and Research in Education, Vol 8, No 2 (2013)
openaire +3 more sources
UJI MASA SIMPAN PELET TRICHODERMA HARZIANUM DAN KEMAMPUANNYA DALAM MENGHAMBAT PERKEMBANGAN PENYAKIT LAYU FUSARIUM PADA BIBIT TOMAT [PDF]
, 2018 RINGKASANTomat (Solanum lycopersicum) merupakan salah satu komoditas pertanian yangditanam secara luas di seluruh dunia, termasuk di Indonesia, karena memiliki rasa yang khas dan enak, juga memiliki nilai gizi seperti sumber vitamin A dan C yang ...
RIZKA MUSFIRAH
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Evaluating the Impact of Post-Emergence Weed Control in Honeybee Colonies Located in Different Agricultural Surroundings. [PDF]
Insects, 2021 Macri IN +4 more
europepmc +1 more source
Performance of Agronomic Crop Varieties in Alaska 1978 –2002 [PDF]
, 2004 There is no such thing as the perfect variety for Alaska. Some varieties are adapted to a wide range of climatic and geographic locations, while others are more specific in their adaptation.
Knight, Charles W. +1 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source