Results 111 to 120 of about 127,816 (300)

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

Clinical and epidemiological profile of patients who seek post-exposure prophylaxis after sexual exposure to HIV and their adherence to the medication regimen in a specialized center in Cascavel, Paraná, Brazil

DST, 2019
Introduction: Post-Exposure Prophylaxis (PEP) is part of a new strategy for the prevention of Human Immunodeficiency Virus transmission adopted by the Brazilian Ministry of Health.
Vania Orlandi, Dilson Fronza, Douglas Soltau Gomes, Josana Aparecida Dranka Horvath, Winny Hirome Takahashi Yonegura   +4 more
doaj  

Pre-existing invasive fungal infection is not a contraindication for allogeneic HSCT for patients with hematologic malignancies: a CIBMTR study. [PDF]

, 2017
Patients with prior invasive fungal infection (IFI) increasingly proceed to allogeneic hematopoietic cell transplantation (HSCT). However, little is known about the impact of prior IFI on survival.
Aljurf, M, Auletta, JJ, Battiwalla, M, Boeckh, MJ, Brazauskas, R, Chen, M, Dvorak, CC, Gea-Banacloche, J, Geroge, B, Guinan, EC, Hale, GA, Lazarus, HM, Lee, J-W, Liesveld, JL, Lindemans, CA, Martino, R, Maziarz, RT, McLeod, AA, Ramanathan, M, Reddy, V, Riches, ML, Savani, BN, Smith, FO, Strasfeld, L, Taplitz, RA, Ustun, C, Wingard, JR   +26 more
core  

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

, 2015
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip, Gerardin, Jaline, Wenger, Edward A.   +2 more
core   +1 more source

Delays in rabies post-exposure prophylaxis abroad

Journal of Travel Medicine
Abstract Background Many travellers sustain an animal-associated injury (AAI) that may lead to rabies. To avert infection the WHO recommends starting post-exposure prophylaxis (PEP) within 24 hours of the AAI. Many travellers experience PEP delay (60%). The reason for this is unclear, but delay
Feij, M. de, Luppino, F.S., Visser, L.G., Vlot, J.A.   +3 more
openaire   +3 more sources

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

Enhancing Human Post‐Exposure Rabies Prophylaxis in Canine Rabies Endemic Regions With an Interactive Web Solution

Public Health Challenges
Despite the availability of effective biologics, rabies continues to impact several low‐ and middle‐income countries. More than 50,000 people succumb to rabies every year due to the lack of timely and appropriate post‐bite care.
Aniruddha V. Belsare, Deborah J. Briggs, Gyanendra Gongal, Reeta S. Mani, Charles E. Rupprecht   +4 more
doaj   +1 more source

Emergent informal use of doxycycline post- and pre-exposure prophylaxis among men who have sex with men and transgender and gender diverse people, the Netherlands, 2024

Eurosurveillance
BACKGROUND Doxycycline post-exposure and pre-exposure prophylaxis (doxyPEP/PrEP) to prevent sexually transmitted infections (STIs) is not part of standard practice in the Netherlands but may be used informally (without prescription).
Vita W Jongen
doaj   +1 more source