Results 171 to 180 of about 65,817 (260)

Single‐stage revision for chronic fistulized infected total knee arthroplasty achieves infection‐free survival comparable to non‐fistulized cases

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The presence of a sinus tract in chronic periprosthetic joint infection (PJI) has traditionally been considered a contraindication to single‐stage total knee arthroplasty (TKA) revision. However, an increasing number of surgeons are now performing single‐stage revisions in this context, despite limited comparative data.
Arthur Barbaret, Joseph Jacquet, Patrice Wong, David Zhu, Florian Collignon, Thomas Oberle, Louis Lajoinie, Clement Ferri, Kamel Rouizi, Gregoire Vaz, Andrea Fernandez, Sibylle Bevilacqua, Olivier Roche   +12 more
wiley   +1 more source

Hepatitis B vaccination and post-exposure prophylaxis in healthcare workers - a comparative analysis of national and supranational recommendations. [PDF]

GMS Hyg Infect Control
Ciochina D, Stranzinger J, Nienhaus A, Diel R.   +3 more
europepmc   +1 more source

Sport participation after isolated distal femoral osteotomy in young patients: High return‐to‐sport rates and predictive role of preoperative activity level

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The present study aimed to assess return to sport (RTS) rate, activity level and return to work (RTW) in young, physically active patients who underwent isolated distal femoral osteotomy (DFO) for lateral knee pain and valgus malalignment.
Gian Andrea Lucidi, Federico Maria Adravanti, Claudio Rossi, Margherita Bonaiuti, Stefano Di Paolo, Alberto Grassi, Stefano Zaffagnini   +6 more
wiley   +1 more source

Preclinical evaluation of long-acting cabotegravir and rilpivirine for HIV post-exposure prophylaxis in a macaque model. [PDF]

EBioMedicine
Srinivasan P, Zhang J, Edwards T, Dinh C, Green A, Little D, Singletary T, Mendoza M, Pan Y, Deyounks F, Johnson R, Lipscomb J, Kourtis AP, Heneine W, García-Lerma JG, Smith JM.   +15 more
europepmc   +1 more source

Four general‐purpose large language models (ChatGPT‐5, Claude 4, Grok 4 and Gemini 2.5) show comparable performance in specialised total knee arthroplasty clinical questions

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate and compare the performance of four general‐purpose large language models (LLMs) (ChatGPT‐5, Claude 4, Grok 4 and Gemini 2.5) in answering specialised clinical questions related to total knee arthroplasty (TKA) derived from the World Expert Meeting in Arthroplasty (WEMA). Methods This is a cross‐sectional comparative study.
Oriol Pujol, Robert Ferrer, Alex Coelho, Felix C. Oettl, Balint Zsidai, Joan Leal‐Blanquet, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

Circulating Antibody's Role During Post-Exposure Prophylaxis, and Beyond for Rabies: A Review. [PDF]

Vaccines (Basel)
Chen Q, Cai L, Lv X, Liu S, Liu C, Liu J, Liu X, Yin W, Wang C, Zhu Z.   +9 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Advances and challenges in experimental models for Epstein–Barr virus research

mLife, EarlyView.
Abstract Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ‐herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Experimental models are pivotal for unraveling the infection and pathogenesis mechanisms, life cycle regulation, as well as development and ...
Gulimire Wufuer, Jiabao Tang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +5 more
wiley   +1 more source

Do we need a regulatory path for HIV post-exposure prophylaxis? [PDF]

J Int AIDS Soc
Miller V, Schaefer R.
europepmc   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source