Results 61 to 70 of about 918,872 (308)
Metals, 2023 The non-uniformity of microstructures and mechanical properties across a whole welded joint is a crucial factor leading to its weakening performance and premature failure.
Bin Yang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Experimental identification of the process inffluences on gear distortion during heat treatment [PDF]
, 2013 Heat treatment is widely used in automotive industry to improve mechanical properties of workpieces. It also generates side effects such as geometrical distortions.
BIGOT, Regis +3 more
core
Accurate non-contact temperature measurements during surface heat-treatment processes
, 2022 S.182-191Die genaue Temperaturführung beim Randschichthärten ist von entscheidender Bedeutung, um die Nutzeigenschaften innerhalb enger Grenzen gezielt einzustellen.
Bonß, Steffen +5 more
core +1 more source
Effect of Shortened Post Weld Heat Treatment on the Laser Welded AA7075 Alloy
Metals, 2022 The present study provides an overview of previous studies on the welding of the AA7075-T6 aluminum alloy, followed by an investigation of the influence of short-time solution annealing on the mechanical properties of the weld. Conventional laser welding
Timon Suckow +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Teshugang, 2020 The microstructure and properties of the heat affected coarse grain zone of steel 07MnCrMoVR with post¬weld heat treated at 460 ~ 660 °C for 2 h are analyzed by means of optical microscope, scanning microscope, transmission electron microscope and impact
冯路路, 乔文玮, 鲁修宇, 周峰
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Metalurgija, 2013 The present work has been conducted in order to determine the influence of heat treatment on the wear and corrosion behaviours of a gray cast iron substrate coated with a Ni base coating deposited by HVOF thermal spray.
A. Öz +5 more
doaj
VARIASI TEMPERATUR POST HEAT TREATMENT ELECTROLESS NICKEL PADA FCD 500
Seminar Keinsinyuran Program Studi Program Profesi Insinyur, 2021 Pelapisan electroless nickel merupakan jenis pelapisan autocatalytic yang dapat digunakan sebagai alternatif pengganti hard chromium plating disebabkan pemakaian larutan elekrolit yang merupakan limbah berbahaya. Pada pengujian ini dilakukan pelapisan electroless nickel menggunakan larutan nickel phosphorus pada base metal FCD 500, dengan variasi waktu
Ike Widyastuti, Ali Mokhtar
openaire +1 more source