Results 161 to 170 of about 6,663,865 (308)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Other title: Report of the Legislative Post Audit Committee to the 1975 Session of the Kansas Legislature

open access: yes, 1974
"December 31, 1974."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Pre-post implementation policy support for warnings on cigarette filters in Canada among adults who smoke cigarettes. [PDF]

open access: yesTob Control
Hackworth EE   +7 more
europepmc   +1 more source

Enterprise resource planning post-implementation assimilation challenge : an integrative framework for a better post-implementation assimilation

open access: yes, 2009
Cette étude s'inscrit dans la recherche émergente sur la post-implémentation des TI et vise à contribuer à la discussion sur l'impact des facteurs contextuels sur le niveau d'assimilation des technologies complexes telles que les systèmes ERP. Compte tenu de la rareté des recherches, cette étude vise aussi à enrichir ce champ de recherche qui a été ...
openaire   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Other title: Report of the Legislative Post Audit Committee to the 1973 Session of the Kansas Legislature

open access: yes, 1972
"December 31, 1972."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

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