Advanced Science, EarlyView.The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan +10 more
wiley +1 more source
A post-marketing study to evaluate the safety and immunogenicity of a quadrivalent influenza split-virion vaccine in elderly people aged 60 years and older. [PDF]
Trop Dis Travel Med VaccinesKou Z +10 more
europepmc +1 more source
Safety and effectiveness of tofogliflozin in elderly Japanese patients with type 2 diabetes mellitus: A subanalysis of a post-marketing study (J-STEP/EL Study). [PDF]
J Diabetes Investig, 2020 Kaku K +6 more
europepmc +1 more source
Descriptive Analysis of Post-marketing Database Studies Before and After the Revision of Good Post-marketing Study Practice2022
openaire
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Safety and Effectiveness of Dulaglutide in the Treatment of Type 2 Diabetes Mellitus: A Korean Real-World Post-Marketing Study. [PDF]
Diabetes Metab JHan J +5 more
europepmc +1 more source
Design of a non-interventional post-marketing study to assess the long-term safety and effectiveness of ocrelizumab in German real world multiple sclerosis cohorts - the CONFIDENCE study protocol. [PDF]
BMC Neurol, 2020 Dirks P +6 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang +13 more
wiley +1 more source
Electrocatalytic C─C Bond Formation Via Cyanide Interception of CO2 Reduction Intermediates
Advanced Science, EarlyView.ABSTRACT Electrochemical CO2 reduction offers a sustainable route to convert greenhouse gas into high‐value‐added chemicals, yet product distributions remain largely limited to simple C1‐C3 molecules. Here, we report a new reaction in which CO2 reduction intermediates undergo direct C‐C coupling with an external carbon nucleophile under electrochemical
Gongbo Liu +10 more
wiley +1 more source
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Advanced Science, EarlyView.Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source